# Takayasu's Arteritis: An Uncommon Cause of Hemorrhagic Stroke in Young Individuals

**Authors:** Ebad-Ur Rehman Syed, Noman Salih, Hidayat Ullah, Abdul Wahab, Muhammad Younas Ali, Muhammad Ayub, Numan Ghani

PMC · DOI: 10.7759/cureus.52301 · Cureus · 2024-01-15

## TL;DR

A rare case of Takayasu's arteritis in a young Asian woman caused a hemorrhagic stroke and was successfully managed with immunosuppressive treatment.

## Contribution

This case study highlights the rare but severe neurological complications of Takayasu's arteritis in young individuals.

## Key findings

- The patient presented with left-sided weakness and seizures due to ischemic infarcts and vasculopathy.
- The patient met multiple ACR criteria for TA with elevated ESR.
- Treatment with prednisolone and cyclophosphamide improved the patient's condition despite initial complications.

## Abstract

The aorta is particularly damaged by Takayasu's arteritis (TA), a rare form of vasculitis. Chest discomfort, exhaustion, fever, elevated blood pressure, heart failure, and stroke can all result from this. Major intimal fibrosis with vascular constriction is the disease's hallmark; although anybody can have it, Asian females in their 20s or 30s seem to be most typically affected. The treatment of a 23-year-old Asian female with Takayasu's arteritis (TA) is discussed in this case study, along with her presentation. Before developing seizures, the patient first showed signs of left-sided weakness and facial droop. Ischemic infarcts and vasculopathy were detected by imaging. The patient fulfilled several American College of Rheumatology (ACR) criteria for TA with a positive erythrocyte sedimentation rate (ESR). During treatment, high-dose prednisolone, cyclophosphamide, and neuroprotective measures were used. The patient's attentiveness and mobility improved despite early complications, such as vascular friability. This case illustrates the difficulties and effective treatment of neurovascular problems connected to TA.

## Linked entities

- **Chemicals:** prednisolone (PubChem CID 5755), cyclophosphamide (PubChem CID 2907)
- **Diseases:** Takayasu's arteritis (MONDO:0017991), hemorrhagic stroke (MONDO:1060199), vasculopathy (MONDO:0005385)

## Full-text entities

- **Diseases:** Ischemic infarcts (MESH:D007238), fibrosis (MESH:D005355), stroke (MESH:D020521), facial droop (MESH:D005153), Chest discomfort (MESH:D013898), weakness (MESH:D018908), elevated blood pressure (MESH:D006973), Hemorrhagic Stroke (MESH:D000083302), exhaustion (MESH:D006359), vasculopathy (MESH:D000090122), TA (MESH:D013625), fever (MESH:D005334), neurovascular problems (MESH:D013901), vasculitis (MESH:D014657), seizures (MESH:D012640), heart failure (MESH:D006333)
- **Chemicals:** prednisolone (MESH:D011239), cyclophosphamide (MESH:D003520)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10865922/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC10865922/full.md

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Source: https://tomesphere.com/paper/PMC10865922