# Cardiac Mass and Cerebrovascular Accident as Primary Manifestations of Churg-Strauss Syndrome

**Authors:** Fariba Abbasi, Ata Abbasi, Alireza Rostamzadeh, Seyede Zohre Banihashemi, Aliakbar Rajabi

PMC · DOI: 10.34172/aim.2023.97 · Archives of Iranian Medicine · 2023-11-01

## TL;DR

A rare case of EGPA presented with a heart mass and stroke, highlighting the importance of heart checks in such patients.

## Contribution

Reports a rare cardiac manifestation of EGPA confirmed by echocardiography and histopathology.

## Key findings

- A large left ventricular granuloma was detected in a patient with EGPA.
- EGPA diagnosis was confirmed through paraclinical and histopathologic findings.
- The case emphasizes the need for routine echocardiography in EGPA patients.

## Abstract

Churg-Strauss syndrome (CSS), recently named eosinophilic granulomatosis with polyangiitis (EGPA), is a rare form of systemic vasculitis with extravascular granulomas occurring in patients with asthma and tissue eosinophilia. We represent a large left ventricular granuloma, confirmed by histopathologic evaluation, detected as a ventricular mass by echocardiography in a 45-year-old asthmatic male who was admitted for a cerebrovascular accident. Paraclinical and histopathologic findings confirmed the diagnosis of EGPA. As cardiac involvement in patients with EGPA is associated with poor prognosis, routine echocardiographic evaluation of these patients is suggested.

## Linked entities

- **Diseases:** Churg-Strauss syndrome (MONDO:0015943), eosinophilic granulomatosis with polyangiitis (MONDO:0015943), asthma (MONDO:0004979), cerebrovascular accident (MONDO:0005098)

## Full-text entities

- **Diseases:** granulomas (MESH:D006099), CSS (MESH:D015267), systemic vasculitis (MESH:D056647), tissue eosinophilia (MESH:D004802), ventricular mass (MESH:C536030), Cerebrovascular Accident (MESH:D020521), EGPA (MESH:D014890), Cardiac Mass (MESH:D006331), left ventricular granuloma (MESH:D018487), asthma (MESH:D001249), asthmatic (MESH:D013224)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10864941/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC10864941/full.md

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Source: https://tomesphere.com/paper/PMC10864941