# Vasopressin-Induced Gangrene of the Bilateral Foot Digits and Right Index Finger Managed With Platelet-Rich Plasma Treatment

## TL;DR

A 20-year-old woman with vasopressin-induced gangrene in her feet and finger was successfully treated with platelet-rich plasma, showing potential for this therapy in similar cases.

## Contribution

This case report introduces platelet-rich plasma infiltration as a novel treatment for vasopressin-induced gangrene.

## Key findings

- PRP infiltration improved tissue perfusion and halted necrosis progression in a vasopressin-induced gangrene case.
- PRP may promote recovery through angiogenesis and tissue regeneration in severe gangrene.
- Further studies are needed to confirm PRP's efficacy as a standard treatment for vasopressin-induced gangrene.

## Abstract

Bilateral foot digit gangrene generated by vasopressin is a serious complication for which management and treatment choices are extremely difficult. This case report presents a case of vasopressin-induced gangrene that was successfully treated with platelet-rich plasma (PRP) infiltration. A 20-year-old female patient came with a history of vasopressin treatment, causing bilateral foot digit gangrene and increasing necrosis. The patient's health quickly declined, and conventional care techniques had no effect on enhancing tissue perfusion or stopping the gangrene from getting worse. In our study, we have chosen to use PRP infiltration as an experimental therapeutic technique in light of the restricted choices available. This case study demonstrates the possibility of PRP infiltration as a cutting-edge and effective treatment for vasopressin-induced bilateral foot digit gangrene. The potential of PRP to stimulate angiogenesis, tissue regeneration, and wound healing is essential for optimizing the patient's results. For vasopressin-induced gangrene, more studies are required to evaluate the efficacy of PRP infiltration as a common therapy approach. This case study highlights the important role that PRP infiltration plays in enhancing tissue perfusion, stopping the advancement of necrosis, and promoting recovery.