# Surgical Management of Severe Mandibular Actinomycosis: Segmental Mandibulectomy and Fibula Free Flap for Optimal Outcomes

## TL;DR

This paper discusses a severe case of mandibular actinomycosis treated with surgery and reconstruction, resulting in good functional and aesthetic outcomes.

## Contribution

The novel contribution is the successful use of segmental mandibulectomy and fibula free flap in treating antibiotic-resistant mandibular actinomycosis.

## Key findings

- Aggressive surgical resection was necessary for antibiotic-resistant mandibular actinomycosis.
- Immediate reconstruction with a fibula-free flap provided favorable functional and aesthetic outcomes.

## Abstract

Actinomycosis is a chronic, suppurative, granulomatous bacterial infection primarily associated with Actinomyces israelii. The condition can be categorized into three distinct clinical types based on the affected anatomical region: cervicofacial, pulmonary, or abdominopelvic actinomycosis. The standard treatment for actinomycosis involves antibiotic therapy, with an empiric penicillin regimen as the first-line approach. Surgical interventions comprise curettage of the affected bone, resection of necrotic tissues, excision of existing sinus tracts, and drainage of abscesses. These procedures are considered a last resort for cases of actinomycosis unresponsive to antibiotic therapy. In this context, we present a case of severely unresponsive actinomycosis that necessitated aggressive surgical resection of the infected mandibular bone, followed by immediate reconstruction using a fibula-free flap. The outcome yielded both favorable functional and aesthetic results.