# A Case of Long-Tract Ileocolic Intussusception Secondary to Well-Differentiated Cecal Adenocarcinoma

**Authors:** Mohamad Ballan, Mahroo Aghababaei, An Guo Michael Chin, Dmitriy Kim

PMC · DOI: 10.7759/cureus.52208 · 2024-01-13

## TL;DR

An 86-year-old woman was diagnosed with a rare case of intussusception caused by a cecal adenocarcinoma, highlighting the importance of considering cancer as a cause in adults.

## Contribution

This case report highlights the rare occurrence of well-differentiated cecal adenocarcinoma as a lead point for intussusception in adults.

## Key findings

- A 2.6 cm solid mass in the cecum was identified as the lead point for ileocolic intussusception.
- Pathological analysis confirmed a T1N0M0 well-differentiated adenocarcinoma with no lymph node involvement.
- The case emphasizes the diagnostic challenge of intussusception in adults due to nonspecific symptoms.

## Abstract

Intussusception denotes the intricate phenomenon wherein one segment of the bowel undergoes invagination or telescoping into its contiguous distal segment. The ensuing invaginated segment may be propelled forward through peristaltic movements, potentially precipitating bowel obstruction or ischemia, culminating in necrosis of the affected bowel segment. Although the precise etiology of intussusception remains elusive, particularly in cases devoid of an identifiable lead point, dysrhythmic contractions and lymphoid hyperplasia have been implicated in the pathophysiology of this condition.

We present the case of an 86-year-old African American female with a past medical history of hypertension and asthma who presented to our emergency room with a seven-day history of worsening abdominal. The pain was described as sharp and intermittent, and it would worsen with every meal or drink. A physical exam demonstrated the right lower quadrant with vague abdominal tenderness, especially below the umbilical region. Computed tomography of the abdomen and pelvis revealed a long segment of ileocolic obstructing intussusception in the ascending colon, with a 2.6 cm solid mass serving as a lead point. Swift intervention ensued with an urgent exploratory laparotomy, culminating in a right hemicolectomy to excise the intussuscepted segment of the bowel. The pathological examination identified a well-differentiated adenocarcinoma of the cecum, categorized as T1N0M0, with all 20 resected lymph nodes yielding negative results.

This illustrative case presents a unique insight into a patient with ileocolic obstructing intussusception, caused by a well-differentiated adenocarcinoma acting as the lead point, a relatively uncommon occurrence in adults. Diagnosing intussusception in adults is challenging due to its nonspecific symptoms, which are similar to those of various other gastrointestinal disorders. Therefore, it is crucial for medical providers to be acutely aware of the possibility that adenocarcinoma can trigger obstructing intussusception in various parts of the bowel.

## Linked entities

- **Diseases:** asthma (MONDO:0004979), adenocarcinoma (MONDO:0004970), intussusception (MONDO:0007835)

## Full-text entities

- **Diseases:** Intussusception (MESH:D007443), ischemia (MESH:D007511), lymphoid hyperplasia (MESH:D019310), hypertension (MESH:D006973), Ileocolic Intussusception (MESH:D003424), gastrointestinal disorders (MESH:D005767), abdominal tenderness (MESH:D000007), asthma (MESH:D001249), necrosis (MESH:D009336), bowel obstruction (MESH:D012778), Cecal Adenocarcinoma (MESH:D002429), adenocarcinoma (MESH:D000230), pain (MESH:D010146)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10860693/full.md

---
Source: https://tomesphere.com/paper/PMC10860693