Aortic valve-sparing variants are getting closer
Marek J. Jasinski

Abstract
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TopicsCardiac Valve Diseases and Treatments · Aortic Disease and Treatment Approaches · Infective Endocarditis Diagnosis and Management
To the Editor:
Interest in valve-sparing operations is undoubtedly ongoing, as illustrated by recent articles in AATS journals: JTCVS Techniques,1 Operative Techniques in Thoracic and Cardiovascular Surgery,2 and the Journal of Thoracic and Cardiovascular Surgery.3 A recent meta-analysis confirmed that valve-sparing aortic root replacement with reimplantation is associated with better overall survival and lower risk of need for reintervention compared with valve-sparing aortic root replacement with remodeling. Regarding overall survival, we observed a time-varying effect that favored the reimplantation technique up to 4 years of follow-up, but not beyond this time point, apparently losing the early benefit of Dacron prosthesis stabilization.4 Moreover, the results are not homogenous across the different phenotypes with bicuspid aortic valve as a risk factor shown recently by Sharma and colleagues.3 There are several issues related to aortic valve reimplantation that may be responsible. They are focusing on the importance of stabilizing the virtual basal ring (VBR) and the ventriculo-aortic junction (VAJ) at the same time. The observations include inconsistent interference between the VAJ and the Dacron prosthesis along the annular circumference and pseudoaneurysm formation risk,5 a significant tilt in the aortic root axis between the sinotubular junction and VAJ,6 and dynamic changes in the aortic annulus level, area and shape during cardiac systole-diastole action,5 and size and shape progression at median follow-up.7^,^8
An interesting approach to the reimplantation procedure was presented recently in JTCVS Techniques by Woo and colleagues1 from Stanford. They embraced elements of remodeling by differing from the horizontal plane due to mitral curtain, bundle of His or VAJ, and close approximation to left-non, right-non, and left-right commissures, respectively.
On the other hand, it has been suggested that stabilizing the VBR is essential for a secure repair.9 To address this, different models of VBR stabilization have been developed. Among them, the internal annuloplasty, by definition, allows stabilization of the basal ring, certainly to reduce further dilatation, maintaining at the same time subcommissural triangles due to the crown-shaped 3-pointed structure of the ring, thus stabilizing the sinuses of Valsalva by virtue of coupling VAJ and VBR planes.8
The idea of combining both internal annuloplasty with the internal anatomic annuloplasty ring and external Dacron ring or prosthesis can be successfully adopted and is shown in Figure 1, as well as demonstrated by the tutorial,10 featuring the remodeling elements. This embraces concepts of VAJ remodeling and prosthesis trimming during reimplantation (Figure 2) and complete circular annuloplasty, both internally and externally,popularized by Nawaytou and colleagues9 and promoted by G.El Khoury9 and T. David.11Figure 1. Concept of tailored external annuloplasty with anatomic inflow line.Figure 2. Tailored graft during reimplantation- author's technique.12
Stabilization and relative adjustment of VBR, VAJ, and sinotubular junction allow for physiological transmission of movements or cross-talk between the ventricle and the root with emphasis on the role of unobstructed root systolic root dilatation causing horizontal stretch and triangular shape of leaflets, according to Yacoub and colleagues.8 This implies tailoring the surgical approach to individual physiology translating into adopting different methods. It encourages us to remain open-minded and explore different techniques to improve the end result of aortic valve repair.
Conflict of Interest Statement
Dr Jasinski: Medtronic and Corcym.
The Journal policy requires editors and reviewers to disclose conflicts of interest and to decline handling or reviewing manuscripts for which they may have a conflict of interest. The editors and reviewers of this article have no conflicts of interest.
The reference list from the paper itself. Each links out to its DOI / PubMed record.
- 1Zhu Y.Woo Y.J.The 170/190 commissure positioning technique for bicuspid aortic valve repair using valve sparing aortic root replacement JTCVS Tech 182023373910.1016/j.xjtc.2023.01.01237096113 PMC 10122148 · doi ↗ · pubmed ↗
- 2Preventza O.Huu L.A.Coselli J.S.Straightforward contemporary step-by-step approach to aortic root replacement with valve-sparing tricuspid aortic valve repair Op Tech Thorac Cardiovasc Surg 2820238091
- 3Sharma V.J.Kangarajah A.Yang A.Kim M.Seevayanagam S.Matalanis G.Valve sparing aortic root replacement: long-term variables significantly associated with mortality and morbidity J Thorac Cardiovasc Surg November 21, 2023[Epub ahead of print]. 10.1016/j.jtcvs.2023.11.02737992962 · doi ↗ · pubmed ↗
- 4SáM.P.Jacquemyn X.Awad A.K.Brown J.A.Chu D.Serna-Gallegos D.Valve-sparing aortic root replacement with reimplantation vs remodeling: a meta-analysis Ann Thorac Surg 202310.1016/j.athoracsur.2023.08.01837831047 · doi ↗ · pubmed ↗
- 5Liu R.H.Fraser C.D.III Zhou X.Cameron D.E.Vricella L.A.Hibino N.Pseudoaneurysm formation after valve sparing root replacement in children with Loeys-Dietz syndrome J Card Surg 3320183393432972603710.1111/jocs.13709 · doi ↗ · pubmed ↗
- 6Irace F.G.Chirichilli I.Salica A.D’Aleo S.Wolf L.G.Garufi L.Aortic root anatomy after aortic valve reimplantation J Thorac Cardiovasc Surg 1652023133513423398580510.1016/j.jtcvs.2021.03.115 · doi ↗ · pubmed ↗
- 7Valdis M.Thain A.Jones P.M.Chan I.Chu M.W.Multimodal imaging of aortic annulus and root geometry after valve sparing root reconstruction Ann Cardiothorac Surg 8201936237110.21037/acs.2019.05.0931240180 PMC 6562094 · doi ↗ · pubmed ↗
- 8Yacoub M.H.Kilner P.J.Birks E.J.Misfeld M.The left ventricle outflow and root: a tale of dynamism and cross talk Ann Thorac Surg 681999 S 37S 431050599010.1016/s 0003-4975(99)00745-6 · doi ↗ · pubmed ↗
