# Hodgkin Lymphoma Involving the Brain: Report of a Rare Case

## TL;DR

This paper reports a rare case of Hodgkin lymphoma affecting the brain in a 31-year-old man previously treated with anti-CD30 antibodies.

## Contribution

The novelty lies in presenting a unique intracranial Hodgkin lymphoma case following anti-CD30 therapy.

## Key findings

- Intracranial Hodgkin lymphoma is extremely rare and requires careful investigation.
- The patient had been previously treated with anti-CD30 antibodies.
- Diagnosis relied on morphological and immunohistochemical analysis of biopsy specimens.

## Abstract

Hodgkin lymphoma (HL) is a systemic neoplastic process that mostly affects the lymph nodes of the cervical, supraclavicular, and mediastinal regions. The involvement of the central nervous system by HL is rare, and the diagnosis is typically determined based on distinct morphological and immunohistochemical analyses performed on tissue biopsy specimens. Intracranial HL is so scarce that any of the intracranial space-occupying pathology in a patient with established HL must be meticulously investigated to rule out a secondary disease process. Here, we report a unique case of intracranial HL in a 31-year-old African American male who was previously treated with anti-CD30 antibodies.