# Multiple Cardiac Diseases Involving the Aortic Arch: Beating Heart Debranching, and Normothermic Arch Replacement: A Case Series

**Authors:** Alessandro Motta, Cristian Scarpari, Ermelinda Borrelli, Francesco Formica

PMC · DOI: 10.3390/jcm13030732 · Journal of Clinical Medicine · 2024-01-26

## TL;DR

This paper presents a new surgical approach for treating complex aortic and heart diseases that reduces risks and improves outcomes.

## Contribution

A novel 'debranching first' surgical technique for aortic arch disease combined with cardiac procedures is introduced and evaluated.

## Key findings

- The approach reduced the need for hypothermia and cardiopulmonary bypass time.
- Early mortality was 8.3% with no permanent neurological events in 12 patients.
- The method shows promise for high-risk patients with complex aortic and cardiac diseases.

## Abstract

(1) Background: Conventional open surgery is still the gold standard for aortic arch disease, and despite recent developments in optimizing strategies for neuroprotection, distal organ perfusion, and myocardial protection, aortic arch replacement is still associated with high morbidity and mortality rates. (2) Methods: We present our case series of 12 patients undergoing surgical management of multiple cardiac diseases involving the aortic arch. In this single-center study, we report our initial experience over a five-year period (from December 2018 to October 2023) with the use of a “debranching first” technique for the supra-aortic vessels of a beating heart, followed by the cardiac step addressing proximal diseases, and a final distal step treating the aortic arch. This strategy aims to minimize cardiac, cerebral, and peripheral ischemia. (3) Results: Six patients underwent aortic root replacement with either Bentall (n = 4) or valve-sparing aortic root (David procedure) (n = 2). The mean nasopharyngeal temperature was 34 °C and the mean cardiocirculatory arrest was 14.3 min. The early mortality was 8.3% (1 patient); no patient experienced a permanent neurologic event. (4) Conclusions: In patients with complex aortic disease and concomitant cardiac disease, this approach reduces the need for hypothermia and decreases cardiopulmonary bypass time and myocardial arrest time and therefore could represent a valid surgical option, even in high-risk patients.

## Linked entities

- **Diseases:** cardiac disease (MONDO:0005267)

## Full-text entities

- **Diseases:** Cardiac Diseases (MESH:D006331), neurologic event (MESH:D002318), hypothermia (MESH:D007035), myocardial arrest (MESH:D006323), aortic arch disease (MESH:D001015), aortic disease (MESH:D001018), cardiac, cerebral, and peripheral ischemia (MESH:D002545)
- **Chemicals:** Bentall (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC10856784/full.md

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Source: https://tomesphere.com/paper/PMC10856784