# Differences in Functional Capacity between Oncologic and Non-Oncologic Populations: Reference Values

## TL;DR

This study compares physical function and body composition in cancer patients and non-cancer individuals to establish baseline values for better clinical care.

## Contribution

The study provides age-specific baseline values for functionality in cancer patients, improving clinical assessment and management.

## Key findings

- Cancer patients showed significant differences in functionality and body composition compared to non-cancer individuals.
- Age-specific baseline values were established to guide clinical assessments for cancer patients.
- The findings suggest improved clinical decision-making and frailty management in oncology.

## Abstract

This study is focused on the fact that in the context of increasing global aging and cancer diagnoses, additional challenges arise in clinical care. Adequate functionality and body composition are key to coping with antineoplastic treatment, which can lead to better treatment tolerance, survival, and quality of life. This is a cross-sectional comparative study focused on the assessment and comparison of body composition and functionality between cancer patients and a reference population, with the aim of establishing meaningful baseline values. Techniques such as manual dynamometry, the Five-Times Sit-to-Stand test, and bioimpedance were used to collect data from 374 oncologic patients and 1244 reference individuals. The results reveal significant disparities in functionality and body composition among participants, and provide age group-specific adjusted baseline values for those diagnosed with cancer. These findings may have crucial clinical implications for applying particular cut-off points designed for this population group, which makes the assessment process faster and more accurate, enhances the capacity of medical personnel to act quickly, and improves the management of frailty in cancer patients.