# First-Trimester Pregnancy Loss Due to Condyloma Acuminata: A Twisted Tale of Gravidity

**Authors:** Jyotsna Potdar, Apoorva Dave, Swati M Dahiphale

PMC · DOI: 10.7759/cureus.51847 · 2024-01-08

## TL;DR

This paper discusses a case where a pregnant woman's first trimester was complicated by condyloma acuminata, a condition linked to HPV, which can increase the risk of pregnancy loss.

## Contribution

The paper presents a specific clinical case highlighting the challenges of managing HPV-related condyloma acuminata during early pregnancy.

## Key findings

- HPV-induced condyloma acuminata can grow rapidly during pregnancy due to hormonal influences.
- Infections like HPV during pregnancy may increase the risk of spontaneous abortion and preterm delivery.
- Treatment of such conditions in the first trimester may pose additional risks to the pregnancy.

## Abstract

The human papillomavirus can induce condyloma acuminata, a benign papillomatous squamous growth with a fibrovascular core that arises in the vaginal canal. These illnesses typically afflict women who are fertile and are frequently encountered during pregnancy, manifesting with a variety of symptoms. The influences of hormones and vaginal secretions cause the lesion to expand quickly during pregnancy. Viral infections are known to be one risk factor for threatening abortions. Infection with human papillomavirus (HPV) during pregnancy has been associated with a risk for spontaneous abortion, preterm delivery, and abnormalities in the placenta. There are many therapeutic approaches available to address the disease; however, it is still unclear which one is the most successful. Additionally, organogenesis is crucial throughout the first trimester, and treatment during this period may elevate the risk of spontaneous abortion. Here, we describe the case of a young woman who experienced vaginal lesions during the first trimester of her pregnancy.

## Full-text entities

- **Diseases:** Condyloma Acuminata (MESH:D003218), preterm delivery (MESH:D047928), Infection (MESH:D007239), abortion (MESH:D000026), abnormalities in the placenta (MESH:D010922), Viral infections (MESH:D014777), Pregnancy Loss (MESH:D000022)
- **Species:** Human papillomavirus (species) [taxon 10566], Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC10852529/full.md

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Source: https://tomesphere.com/paper/PMC10852529