# Idiopathic Megaduodenum in a Teenager: A Case Report

**Authors:** Anthony N Eze, Akachukwu N Eze, Chinecherem M Chime, Fengming Chen, Dimitrios Moris, Robin Schmitz, Tamara N Fitzgerald

PMC · DOI: 10.7759/cureus.51930 · 2024-01-09

## TL;DR

A teenage girl with a rare condition called idiopathic megaduodenum underwent multiple surgeries and eventually recovered after treatment.

## Contribution

This case report highlights the diagnostic and surgical challenges of idiopathic megaduodenum in adolescents.

## Key findings

- Megaduodenum was diagnosed via contrast radiography and confirmed during exploratory laparotomy.
- The patient required multiple surgeries due to complications like duodenal volvulus and adhesions.
- Histopathological analysis failed to identify a specific cause for the megaduodenum.

## Abstract

Megaduodenum is a rare clinical syndrome characterized by significant duodenal dilation, elongation, and hypertrophy. Given its rarity and nonspecific clinical manifestations, megaduodenum may be misdiagnosed, leading to delays in surgical care and increased morbidity. We describe a case of idiopathic megaduodenum in a teenage Caucasian female, who presented with a five-year history of halitosis, recurrent belching, bloating, nausea and vomiting, and postprandial epigastric abdominal pain. She was diagnosed with megaduodenum by dramatic findings on contrast radiography. She developed a duodenal volvulus necessitating emergency exploratory laparotomy, during which a duodenal plication and a side-to-side duodenojejunostomy were performed. Exploratory laparotomy and histopathological analysis were unrevealing of any definitive abnormalities to explain her megaduodenum. Postoperatively, she developed two early small bowel obstructions, both from subsequent adhesions requiring repeat laparotomy with adhesiolysis. She has subsequently recovered without incident. Diagnosis and accurate classification of megaduodenum requires surgical exploration with a full-thickness biopsy and subsequent histopathologic analysis to rule out obstructive or functional disorders of the duodenum. Treatment of megaduodenum depends on the underlying cause and degree of duodenal distention. It is crucial that clinicians are knowledgeable of the various surgical options, their indications, and the potential postoperative complications that may arise.

## Full-text entities

- **Diseases:** obstructive or functional disorders of the duodenum (MESH:D004379), duodenal dilation (MESH:D004382), Idiopathic Megaduodenum (MESH:C536139), postprandial epigastric abdominal pain (MESH:D015746), halitosis (MESH:D006209), adhesions (MESH:D000267), belching (MESH:D004884), vomiting (MESH:D014839), hypertrophy (MESH:D006984), nausea (MESH:D009325), duodenal volvulus (MESH:D045822), bowel obstructions (MESH:D012778), bloating (MESH:C535647)

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10851044/full.md

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Source: https://tomesphere.com/paper/PMC10851044