# Regional spread of an atypical ESBL-producing Escherichia coli ST131H89 clone among different human and environmental reservoirs in Western Switzerland

## TL;DR

A new antibiotic-resistant E. coli strain spread across human and environmental settings in Western Switzerland from 2017 to 2020.

## Contribution

Identifies a novel ESBL-producing E. coli subclone (ST131H89) and its regional spread across multiple reservoirs.

## Key findings

- The ST131H89 subclone was found in long-term care facilities, the general population, and environmental water sources.
- Molecular surveillance revealed the inter-regional spread of this antibiotic-resistant E. coli strain.
- The study emphasizes the need for monitoring antibiotic resistance in both healthcare and community settings.

## Abstract

We describe the inter-regional spread of a novel ESBL-producing Escherichia coli subclone (ST131H89) in long-term care facility residents, general population, and environmental water sources in Western Switzerland between 2017 and 2020. The study highlights the importance of molecular surveillance for tracking emerging antibiotic-resistant pathogens in healthcare and community settings.