# Gradenigo Syndrome: A Case Report of a Rare Complication of Otitis Media

**Authors:** Zainab Ali, Sajdah Alhantoosh, Zaynab Albaqal, Rawan Alkhudaimi, Ahlam S Alharbi, Tareq A Hamad

PMC · DOI: 10.7759/cureus.51865 · Cureus · 2024-01-08

## TL;DR

This case report describes a rare complication of middle ear infection called Gradenigo syndrome, highlighting the importance of early diagnosis and treatment.

## Contribution

The paper adds to the clinical understanding of Gradenigo syndrome through a detailed case report and emphasizes the need for improved diagnostic and therapeutic approaches.

## Key findings

- A 38-year-old female presented with facial pain, otalgia, and diplopia due to Gradenigo syndrome.
- Antibiotics and myringotomy led to a successful clinical outcome.
- The case underscores the need for structured diagnostic and therapeutic strategies for this rare condition.

## Abstract

Otitis media, a common inflammation of the middle ear, frequently complicates upper respiratory infections. Gradenigo's syndrome, a rare complication, manifests as suppurative otitis media, abducens nerve palsy, and severe trigeminal nerve pain. Prompt recognition is vital because of the proximity of the infection to critical neurovascular structures. We present the case of a 38-year-old female who presented with facial pain, otalgia, and diplopia following an upper respiratory infection. Examination revealed facial weakness and abducens nerve palsy. Laboratory results showed elevated inflammatory markers. Imaging confirmed middle ear involvement. Antibiotics were initiated, and myringotomy was performed, resulting in a successful outcome. This case report contributes to understanding Gradenigo's syndrome's clinical nuances, emphasizing the necessity of a structured diagnostic and therapeutic approach. Ongoing research is crucial for refining diagnostic criteria, optimizing treatment, and enhancing pathophysiological understanding. Increased medical education is imperative to ensure early detection and improved patient outcomes.

## Linked entities

- **Diseases:** otitis media (MONDO:0005441)

## Full-text entities

- **Diseases:** facial weakness (MESH:D018908), diplopia (MESH:D004172), Gradenigo Syndrome (MESH:D059270), inflammatory (MESH:D007249), facial pain (MESH:D005157), abducens nerve palsy (MESH:D020434), involvement (MESH:C564676), upper respiratory infection (MESH:D012141), Otitis Media (MESH:D010033), trigeminal nerve pain (MESH:D009437), infection (MESH:D007239), otalgia (MESH:D004433)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC10848083/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10848083/full.md

## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC10848083/full.md

---
Source: https://tomesphere.com/paper/PMC10848083