# Bright lights, big synapses: fluorescent proteins let neurons shine

**Authors:** Brian D. Ackley

PMC · DOI: 10.1186/s12915-023-01808-7 · 2024-02-05

## TL;DR

Fluorescent proteins help scientists see neurons and synapses in living brains, leading to new discoveries.

## Contribution

The paper highlights new insights into synapses using genetically encoded fluorescent molecules in living organisms.

## Key findings

- Fluorescent proteins have transformed the study of neurons and synapses.
- Genetically encoded fluorescent molecules provide new understanding of synapses in living organisms.

## Abstract

The availability of fluorescent proteins to visualize neurons and synapses has revolutionized our understanding of these key structures in brains. Here, I will discuss the new insights gleaned from the use of genetically encoded fluorescent molecules to study synapses inside living organisms.

## Full-text entities

- **Genes:** unc-2 (Voltage-dependent calcium channel type A subunit alpha-1) [NCBI Gene 180570], lin-14 (Protein lin-14) [NCBI Gene 181337], syd-2 (Liprin-alpha) [NCBI Gene 181255], dlk-1 (Mitogen-activated protein kinase kinase kinase dlk-1) [NCBI Gene 173128]
- **Diseases:** paralysis (MESH:D010243), synapse degeneration (MESH:D009410), synapse defective (MESH:D000013), degenerative diseases (MESH:D019636), movement defect (MESH:D020820)
- **Chemicals:** calcium (MESH:D002118), silver (MESH:D012834), reactive oxygen (-)
- **Species:** C. elegans [taxon 328850], Caenorhabditis elegans (species) [taxon 6239]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC10845595/full.md

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Source: https://tomesphere.com/paper/PMC10845595