# Contexts of care for people with differences of sex development: Diversity is still missing in the laboratory routine

## TL;DR

This paper discusses how current medical practices for DSD still rely on outdated binary systems, neglecting the diversity of sex development.

## Contribution

The paper highlights the lack of updated reference intervals and the need for inclusive clinical practices in DSD care.

## Key findings

- Current laboratory measurements and hormonal therapies for DSD still depend on a binary sex system.
- There is a lack of reference intervals for different forms of DSD, leading to overlooked diversity.
- Transformations in the sex/gender system have introduced new challenges in clinical practice.

## Abstract

The 2006 Chicago consensus statement of management of disorders/difference of sex development (DSD) has achieved advantages in clinical care and diagnosis for patients and families affect by DSD. This article provides a brief overview of contexts of care for physicians, and points out specific challenges in clinical practice that have arisen from the transformations of the sex/gender system in recent years. We focus on the impact of diagnosis and laboratory measurements. Both laboratory measurements and hormonal therapies still depend on the binary system. One problem is the lack of reference intervals for the different forms of DSD, which means that diversity is often neglected. In the following, we will give a brief insight into this complex topic.