# Septic Embolic Encephalitis Following Cardiac Valve Replacement

**Authors:** Dallin Judd, Jake Oldham, James Lish

PMC · DOI: 10.7759/cureus.51628 · Cureus · 2024-01-03

## TL;DR

A 48-year-old man with a history of heart valve replacement developed a rare brain infection, highlighting the importance of imaging and timely treatment.

## Contribution

This case report highlights septic embolic encephalitis as a rare but critical complication following cardiac valve replacement.

## Key findings

- Diagnostic imaging revealed subarachnoid and parenchymal bleeding, cortical infarcts, cerebritis, and meningitis.
- Blood cultures identified Enterococcus, and echocardiogram showed vegetation on the prosthetic valve.
- Abdominal CT scan detected splenic and renal infarcts, indicating systemic embolic spread.

## Abstract

This paper presents a detailed case study of a 48-year-old male who underwent ascending aortic aneurysm repair with a bioprosthetic valve five years prior and subsequently developed septic embolic encephalitis, an infrequent yet critical complication following cardiac valve replacement. The patient exhibited an array of initial symptoms, including generalized weakness, fatigue, fevers, chills, diarrhea, and altered mentation. Microbiological analysis of blood cultures revealed the presence of Enterococcus, and echocardiogram examination demonstrated vegetation on the prosthetic valve. To assess disease progression, diagnostic imaging, including CT scans and MRIs, was conducted at various time points. The imaging results unveiled several abnormalities, including subarachnoid and parenchymal bleeding, cortical infarcts, cerebritis, and meningitis. Additionally, splenic and renal infarcts were observed through an abdominal CT scan. This case report accentuates the paramount role of diagnostic imaging in corroborating suspected septic embolic encephalitis while underscoring the significance of appropriate management of patients with a history of cardiac valve replacement, thereby emphasizing the urgency of timely intervention.

## Linked entities

- **Diseases:** meningitis (MONDO:0021108)

## Full-text entities

- **Diseases:** cortical infarcts (MESH:D007238), splenic and renal infarcts (MESH:D013159), Septic Embolic Encephalitis (MESH:D004660), cerebritis (MESH:D002547), fevers (MESH:D005334), ascending aortic aneurysm (MESH:D000094625), bleeding (MESH:D006470), fatigue (MESH:D005221), diarrhea (MESH:D003967), chills (MESH:D023341), weakness (MESH:D018908), meningitis (MESH:D008580)
- **Species:** Homo sapiens (human, species) [taxon 9606], Enterococcus (genus) [taxon 1350]

## Full text

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## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10837647/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC10837647/full.md

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Source: https://tomesphere.com/paper/PMC10837647