# IMPACT OF HELICOBACTER PYLORI ON EARLY POSTOPERATIVE COMPLICATIONS AFTER SLEEVE GASTRECTOMY: A SYSTEMATIC REVIEW AND META-ANALYSIS

## TL;DR

This study examines whether Helicobacter pylori infection affects post-surgery complications after sleeve gastrectomy, finding no significant differences between infected and non-infected patients.

## Contribution

A systematic review and meta-analysis of HP's impact on early postoperative complications after sleeve gastrectomy.

## Key findings

- No significant difference in overall complications between HP-positive and HP-negative patients.
- HP infection did not significantly increase bleeding or leak rates after surgery.
- The need for routine HP screening before surgery remains unclear.

## Abstract

The impact of Helicobacter pylori (HP) on postoperative outcomes after sleeve gastrectomy (SG) is still controversial. A systematic review and meta-analysis were performed to compare the incidence of early complications after SG between HP-positive and HP-negative patients. Eight retrospective comparative studies were included, comprising 4,877 individuals. The prevalence of HP infection in gastric resected specimens ranged from 7.77 to 43.20%. There were no statistically significant differences between groups for overall complications (OR 1.46; 95%CI 0.95–2.23; p=0.08), bleeding (OR 1.35; 95%CI 0.70–2.60; p=0.38), and leak (OR 1.74; 95%CI 0.80–3.81; p=0.17) rates. The need for routine screening and treatment of HP infection before SG remains ambiguous.