# Size precision in insect eyes

**Authors:** Marco Milán

PMC · DOI: 10.1371/journal.pbio.3002471 · 2024-01-31

## TL;DR

A new study reveals how the size of fruit fly eyes is precisely controlled using signals that regulate cell survival.

## Contribution

The study identifies a morphogen-mediated mechanism that ensures precise eye size in adult fruit flies.

## Key findings

- A morphogen signaling pathway modulates cell survival to regulate eye size in Drosophila.
- This mechanism contributes to the precision of organ size during development.
- The findings provide insight into how organisms achieve proportional organ growth.

## Abstract

The building of fully functional and well-proportioned individuals relies on the precise regulation of the size of each of their constituting organs. A new study unravels a mechanism that confers precision to size regulation of the adult Drosophila eye through morphogen-mediated modulation of cell survival.

## Linked entities

- **Species:** Drosophila (taxon 7215)

## Full-text entities

- **Genes:** put (punt) [NCBI Gene 41772] {aka Act-r, Atr, Atr-II, Atr88CD, AtrII, CG7904}, Stat92E (Signal-transducer and activator of transcription protein at 92E) [NCBI Gene 42428] {aka CG4257, D-STAT, D-Stat, D-stat, D-stat/stat92E, DRODSRC}, hh (hedgehog) [NCBI Gene 42737] {aka CG4637, Dmel\CG4637, Dmhh, Hg, Mir, Mrt}, rpr (reaper) [NCBI Gene 40015] {aka CG4319, Dmel\CG4319, Reaper, anon-WO0162936.19, rp}, Bar (Bar) [NCBI Gene 44798] {aka B, BarH1}, dpp (decapentaplegic) [NCBI Gene 33432] {aka BMP, Bmp, CG9885, DPP-C, Dm-DPP, DmDPP}, hop (hopscotch) [NCBI Gene 32080] {aka 4, CG1594, Dm JAK, DmHD-160, Dmel\CG1594, HD-160}, grim (grim) [NCBI Gene 40014] {aka BcDNA:RE28551, CG4345, Dmel\CG4345, gri, grm}, upd1 (unpaired 1) [NCBI Gene 32813] {aka CG5993, Dmel\CG5993, OS, Os, UPD, Unpaireds}
- **Diseases:** FA (MESH:C565561)
- **Chemicals:** FA (MESH:D005492)
- **Species:** Drosophila melanogaster (fruit fly, species) [taxon 7227]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC10830144/full.md

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Source: https://tomesphere.com/paper/PMC10830144