# Phylogenomics of Dengue Virus Isolates Causing Dengue Outbreak, São Tomé and Príncipe, 2022 **Authors:** Lazismino Lázaro, Doris Winter, Katia Toancha, Adjaia Borges, Anabela Gonçalves, Asmiralda Santos, Marcos do Nascimento, Nilton Teixeira, Yardlene Sacramento Sequeira, Anery Katia Lima, Bakissy da Costa Pina, Andreza Batista de Sousa, Jürgen May, Rosa Maria Afonso Neto, Kathrin Schuldt PMC · DOI: 10.3201/eid3002.231316 · Emerging Infectious Diseases · 2024-02-01 ## TL;DR A 2022 dengue outbreak in São Tomé and Príncipe was caused by a virus strain likely introduced from the Americas. ## Contribution Identification of the dengue virus lineage responsible for the outbreak and its likely origin. ## Key findings - The outbreak was caused by dengue virus serotype 3 genotype III. - The strain is closely related to the GIII-American-II lineage. - The virus was likely introduced from the Americas. ## Abstract We determined that the dengue outbreak in São Tomé and Príncipe during 2022 was caused by dengue virus serotype 3 genotype III. Phylogenomic analyses showed that the outbreak strain was closely related to the newly identified GIII-American-II lineage and that the virus probably was introduced from the Americas. ## Linked entities - **Diseases:** dengue (MONDO:0005502) ## Full-text entities - **Diseases:** infection with the virus (MESH:D014777), febrile disease (MESH:D004194), myalgia (MESH:D063806), Dengue (MESH:D003715), fever (MESH:D005334), headache (MESH:D006261), dengue RDT (MESH:C563738) - **Species:** Dengue virus (no rank) [taxon 12637], Homo sapiens (human, species) [taxon 9606] ## Full text _Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC10826765/full.md ## Figures 1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC10826765/full.md ## References 7 references — full list in the complete paper: https://tomesphere.com/paper/PMC10826765/full.md --- Source: https://tomesphere.com/paper/PMC10826765