# De novo male breast metastases from nasopharyngeal carcinoma: a case report

## TL;DR

This case report describes a rare instance of a 39-year-old man with breast metastasis from nasopharyngeal cancer, highlighting the need for accurate diagnosis and imaging.

## Contribution

This is the first reported case of synchronous male breast metastases from nasopharyngeal carcinoma.

## Key findings

- A 39-year-old male presented with bilateral neck lymph node enlargement and a breast mass.
- Histopathology confirmed synchronous breast metastasis from undifferentiated nasopharyngeal carcinoma.
- The case emphasizes the importance of using CT scans for early metastasis detection in nasopharyngeal cancer.

## Abstract

Nasopharyngeal carcinoma is known for its high potential for regional and distant metastasis. However, breast metastasis is rarely reported.

A 39-year-old Caucasian male presented with bilateral neck lymph node enlargement. Radiological examination with contrast-enhanced computed tomography scan and breast imaging revealed an enhancing mass lesion in the right breast. Histopathology of the nasopharynx mass was suggestive of undifferentiated nasopharyngeal carcinoma. A breast biopsy confirmed the diagnosis of synchronous breast metastasis from the nasopharyngeal carcinoma. We present this study to illustrate that Nasopharyngeal carcinoma can metastasize to the male breast. Furthermore, the high incidence of nasopharyngeal carcinoma metastasis underscores the pressing need to identify effective and safe strategies, emphasizing the importance of utilizing computed tomography scans for metastasis detection.

The present study illustrates the first case of synchronous male breast metastases from nasopharyngeal carcinoma. Thus, it is critical to distinguish between metastatic pathology and coexisting second malignancies to plan appropriate therapy.