# Influence of care modes and social resources on psychotropic medication use in community-dwelling dementia patients

**Authors:** Wei-Chieh Chan, Wen-Fu Wang, Yu-Chun Tung, Ming-Che Chang, Hong-Ting Chan, Kai-Ming Jhang

PMC · DOI: 10.3389/fpsyt.2023.1196801 · Frontiers in Psychiatry · 2024-01-16

## TL;DR

This study explores how care arrangements and social support affect the use of psychotropic medications in dementia patients, aiming to reduce inappropriate prescriptions.

## Contribution

The study identifies modifiable patient and caregiver factors linked to inappropriate psychotropic medication use in dementia patients.

## Key findings

- 39.1% of participants used at least one psychotropic medication categorized as potentially inappropriate.
- Patients with frontotemporal dementia or behavioral symptoms and caregivers with higher depression scores had increased risk of PIM prescriptions.
- Caregivers who were employed or non-spouse had higher odds of PIM prescriptions.

## Abstract

Optimal use of psychotropic medications for people living with dementia is important. By finding potentially modifiable factors, dementia care teams may find solutions to achieve the appropriate use of psychotropic drugs.

This study aimed to elucidate patient and caregiver factors associated with the use of psychotropic drugs listed in the potentially inappropriate medications (PIMs) in community-dwelling people with dementia.

This cross-sectional study enrolled 808 patients newly diagnosed with dementia, and their caregivers, from a dementia clinic at Changhua Christian Hospital. Patient and caregiver characteristics, care mode, and social resource usage were recorded. Multivariate logistic regression was used to identify factors associated with prescribing psychotropic medications.

Of all the participants, 39.1% used at least one of psychotropic medication categorized as PIM. Patients with frontotemporal dementia, with behavior or psychological symptoms, or cared by sole foreign care workers; caregivers with higher depression scores, employed or non-spouse caregivers carried a higher risk of prescription of psychotropic medications listed in PIMs.

Psychotropic drug prescriptions are associated with patient and caregiver factors. Therefore, implementing appropriate interventions, especially those targeting potentially modifiable factors, is important to reduce psychotropic medication use.

## Linked entities

- **Diseases:** dementia (MONDO:0001627), frontotemporal dementia (MONDO:0010857)

## Full-text entities

- **Diseases:** DM (MESH:D009223), care dependency (MESH:D003428), Psychotic symptoms (MESH:D011618), diabetes mellitus (MESH:D003920), FTD (MESH:D057180), PIM (MESH:D000069279), neuropsychiatric symptoms (MESH:D001523), PDD (MESH:D010300), cerebrovascular disease (MESH:D002561), DLB (MESH:D020961), akathisia (MESH:D017109), sleep interruption (OMIM:217095), Pain (MESH:D010146), CKD (MESH:D012080), symptoms (MESH:D012816), Movement Disorder (MESH:D009069), falls (MESH:C537863), delusion (MESH:D063726), Dementia (MESH:D003704), arrhythmias (MESH:D001145), aggression (MESH:D010554), psychotic problems (MESH:D019973), hypertension (MESH:D006973), cardiovascular disease (MESH:D002318), AD (MESH:D000544), Depression (MESH:D003866), agitation (MESH:D011595), Sleep problem (MESH:D012893), CVA (MESH:D020521), anxiety (MESH:D001007), Behavioral and Cognitive Disorders (MESH:D003072), hallucination (MESH:D006212), metabolic syndrome (MESH:D024821), chronic kidney disease (MESH:D051436), hyponatremia (MESH:D007010), behavioral, mood, or sleep problems (MESH:D019964), psychotic, behavioral, mood, and sleep symptoms (MESH:D000341)
- **Chemicals:** paroxetine (MESH:D017374), imipramine (MESH:D007099), PIMN (-), amitriptyline (MESH:D000639), memantine (MESH:D008559)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

27 references — full list in the complete paper: https://tomesphere.com/paper/PMC10824929/full.md

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Source: https://tomesphere.com/paper/PMC10824929