# Paravalvular leak closure using off - label devices: a useful resource

**Authors:** Emilio Herrera, Alberto Navarro, Julián Vanegas, Juan C Ortiz

PMC · DOI: 10.47487/apcyccv.v4i4.302 · Archivos Peruanos de Cardiología y Cirugía Cardiovascular · 2023-12-27

## TL;DR

This paper presents a successful case of using an off-label device to close a paravalvular leak in a mechanical aortic valve.

## Contribution

The novel use of an off-label device for paravalvular leak closure is demonstrated as a viable alternative.

## Key findings

- A percutaneous repair was performed using an interventricular communication closure device.
- The procedure was successful and complication-free during follow-up.
- The approach reduced perioperative risk in a patient with a prior surgical intervention.

## Abstract

Se presenta el caso de un paciente con parafuga valvular de prótesis mecánica en posición aórtica. Por intervención quirúrgica previa reciente se decide llevar a reparo percutáneo para disminuir riesgo perioperatorio, bajo indicación no aprobada (off label) usando un dispositivo para cierre de comunicación interventricular, exitoso y sin complicaciones en el seguimiento.

## Full-text entities

- **Diseases:** Vena contracta (MESH:D013479), protesis valvular (MESH:D006349), NYHA I. (MESH:D006969), Las fugas paravalvulares (MESH:D049310), defectos septales (MESH:D006343), de protesis mecanica (MESH:D005862), FEVI (MESH:C535326), INR (MESH:D000082122), Paravalvular leak (MESH:D019559), edema de miembros inferiores (MESH:D004487), ventricular septal defect (MESH:D006345), endocarditis (MESH:D004696), cirugias cardiacas previas (MESH:D010923)
- **Chemicals:** Se (MESH:D012643), Amplatzer (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10824743/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC10824743/full.md

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Source: https://tomesphere.com/paper/PMC10824743