# Sarcomatoid hepatocellular carcinoma mimics hepatic abscess on contrast‐enhanced ultrasound

**Authors:** Haibo Luo, Xiaoling Leng, Guiwu Chen, Wenqin Liu, Yanhua Xie

PMC · DOI: 10.1002/ccr3.8456 · Clinical Case Reports · 2024-01-29

## TL;DR

A rare liver cancer called sarcomatoid hepatocellular carcinoma can look like a liver abscess in imaging tests, making it hard to diagnose correctly.

## Contribution

This case highlights how SHCC can mimic a hepatic abscess using contrast-enhanced ultrasound and CT scans.

## Key findings

- SHCC was misidentified as a hepatic abscess using imaging techniques.
- The diagnosis was confirmed only after pathological examination.
- SHCC has both epithelial and mesenchymal tumor features.

## Abstract

Sarcomatoid hepatocellular carcinoma (SHCC) is a rare subtype of hepatocellular carcinoma characterized by abdominal pain or persistent fever with an inflammatory reaction. Here, we report a case of SHCC mimicking hepatic abscess described by not only ultrasonography but also computer tomography. SHCC is a rare subtype of hepatocellular carcinoma characterized by epithelial and mesenchymal tumor features with sarcomatoid morphology. Here, we report a case of SHCC described by ultrasonography and computer tomography as well as confirmed by pathological examination.

A 71‐year‐old male patient with a mass located in the liver was described by imaging, including routine abdominal ultrasound, contrast‐enhanced ultrasound, plain computer tomography, and enhanced computer tomography. A diagnosis of sarcomatoid hepatocellular carcinoma (SHCC) was confirmed by pathological examination.

## Linked entities

- **Diseases:** hepatic abscess (MONDO:0700051), hepatocellular carcinoma (MONDO:0007256)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, AFP (alpha fetoprotein) [NCBI Gene 174] {aka AFPD, FETA, HPAFP}, FGB (fibrinogen beta chain) [NCBI Gene 2244] {aka HEL-S-78p}
- **Diseases:** hepatic abscess (MESH:D008100), hepatocellular carcinoma (MESH:D006528), necrosis (MESH:D009336), malignancy (MESH:D009369), portal and hepatic vein thrombosis (MESH:D006502), metastasis (MESH:D009362), infection (MESH:D007239), tenderness (MESH:D063806), SHCC (MESH:D002292), abdominal pain (MESH:D015746), epithelial and mesenchymal tumor (MESH:D002277), inflammatory (MESH:D007249), fever (MESH:D005334)
- **Chemicals:** Hematoxylin (MESH:D006416)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC10823556/full.md

## References

3 references — full list in the complete paper: https://tomesphere.com/paper/PMC10823556/full.md

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Source: https://tomesphere.com/paper/PMC10823556