Flavonoids improve type 2 diabetes mellitus and its complications: a review
Xinrui Yi, Mosi Dong, Naifei Guo, Jinlong Tian, Ping Lei, Song Wang, Yufeng Yang, Yan Shi
TL;DR
This review explores how flavonoids, natural plant compounds, may help manage type 2 diabetes and its complications by reducing blood sugar and inflammation.
Contribution
The paper highlights flavonoids as a promising natural alternative for managing type 2 diabetes and its complications.
Findings
Flavonoids have hypoglycemic, anti-oxidative, and anti-inflammatory effects that benefit T2DM.
They improve glucose and lipid metabolism and reduce insulin resistance.
Flavonoids may serve as a foundation for developing new diabetes medications.
Abstract
The prevalence of type 2 diabetes mellitus (T2DM) is increasing every year. Medications are currently the most common therapy for T2DM. However, these medications have certain adverse effects. In order to find safe and effective ways to improve this disease, researchers have discovered that some natural products can decrease blood sugar. Flavonoids are one of the most essential low molecular weight phenolic chemicals in the plant world, which widely exist in plant roots, stems, leaves, flowers, and fruits. They possess a variety of biological activities, including organ protection, hypoglycemic, lipid-lowering, anti-oxidative and anti-inflammatory effects. Some natural flavonoids ameliorate T2DM and its complications through anti-oxidation, anti-inflammatory action, glucose and lipid metabolism regulation, insulin resistance management, etc. Hence, this review aims at demonstrating the…
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
Click any figure to enlarge with its caption.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7
Figure 8
Figure 9
Figure 10
Figure 11
Figure 12
Figure 13
Figure 14
Figure 15
Figure 16
Figure 17
Figure 18
Figure 19
Figure 20
Figure 21
Figure 22
Figure 23
Figure 24
Figure 25Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsNatural Antidiabetic Agents Studies · Phytochemicals and Antioxidant Activities · Advanced Glycation End Products research