Can Cross-Layer Design Bridge Security and Efficiency? A Robust Authentication Framework for Healthcare Information Exchange Systems
Khalid M. Ezzat, Muhammad El-Saba, and Mahmoud A. Shawky

TL;DR
This paper introduces a cross-layer authentication framework for healthcare information exchange systems that combines cryptographic and physical-layer features with machine learning for secure, efficient, and privacy-preserving device verification.
Contribution
It presents a novel integrated authentication scheme that reduces overhead and enhances privacy in HIE networks by combining PKI, PHY-layer features, and ML-based real-time verification.
Findings
The scheme achieves continuous, lightweight device authentication with reduced cryptographic overhead.
It provides strong security guarantees against impersonation, MitM, replay, and Sybil attacks.
The formal analysis confirms the robustness of the proposed security framework.
Abstract
As healthcare systems become increasingly interconnected, ensuring secure and continuous device authentication in health information exchange (HIE) networks is critical to safeguarding patient data and clinical operations. In this context, this paper proposes a novel cross-layer authentication scheme for HIE networks that integrates cryptographic mechanisms with physical (PHY) layer-based authentication to ensure reliable communication while minimizing computational and communication overheads. The initial authentication phase leverages a traditional public key infrastructure (PKI)-based approach, employing elliptic curve cryptography (ECC) and digital certificates to verify the legitimacy of communicating devices. Simultaneously, it extracts unique hardware-level features such as carrier frequency offset (CFO) and quadrature skewness from the devices. These features are then used to…
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