Directed droplet motion -- Its versatile nature and anticipated applications

TL;DR

This paper reviews the progress and potential applications of directed droplet motion, such as durotaxis, on surfaces with varying properties for use in microfluidics and diagnostics.

Contribution

It summarizes key results and future perspectives in the field of directed droplet motion and its technological applications.

Findings

Directed droplet motion can be achieved using surface property gradients.

Various mechanisms like wettability and Laplace pressure gradients enable droplet transport.

The review highlights potential applications in microfluidics and bio-diagnostics.

Abstract

Applications such as digital microfluidics and bio-diagnostics rely on droplet locomotion. A prominent example of such motion is durotaxis, a phenomenon that requires a stiffness gradient along a surface for the transport of liquids, cells, or other nano-objects. Using surfaces with varying properties in specific directions can be exploited as a universal concept for fluid transport with or without external energy supply. Changes in properties may refer to substrate patterns, Laplace pressure changes, wettability gradients, etc., leading to exciting phenomena, which can be employed in novel applications in various technologies. Here, we report on key results and progress in the area of directed droplet motion over the years, and we provide perspectives and implications for anticipated applications.