BioTrain: Sub-MB, Sub-50mW On-Device Fine-Tuning for Edge-AI on Biosignals
Run Wang, Victor J. B. Jung, Philip Wiese, Sebastian Frey, Giusy Spacone, Francesco Conti, Alessio Burrello, Luca Benini

TL;DR
BioTrain enables full-network fine-tuning of biosignal models on ultra-low-power edge devices, significantly improving accuracy while maintaining minimal memory and power consumption.
Contribution
It introduces a novel framework for full-network on-device fine-tuning of biosignal models under strict power and memory constraints, outperforming existing shallow adaptation methods.
Findings
Achieves up to 35% accuracy improvement over non-adapted baselines.
Enables on-device training throughput of 17 samples/sec for EEG and 85 samples/sec for EOG.
Reduces memory footprint by 8.1x on GAP9 MCU platform.
Abstract
Biosignals exhibit substantial cross-subject and cross-session variability, inducing severe domain shifts that degrade post-deployment performance for small, edge-oriented AI models. On-device adaptation is therefore essential to both preserve user privacy and ensure system reliability. However, existing sub-100 mW MCU-based wearable platforms can only support shallow or sparse adaptation schemes due to the prohibitive memory footprint and computational cost of full backpropagation (BP). In this paper, we propose BioTrain, a framework enabling full-network fine-tuning of state-of-the-art biosignal models under milliwatt-scale power and sub-megabyte memory constraints. We validate BioTrain using both offline and on-device benchmarks on EEG and EOG datasets, covering Day-1 new-subject calibration and longitudinal adaptation to signal drift. Experimental results show that full-network…
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