Representation geometry shapes task performance in vision-language modeling for CT enterography

TL;DR

This study explores how representation choices in vision-language models impact performance on CT enterography analysis, revealing that tissue contrast and pooling methods significantly influence outcomes.

Contribution

It provides the first analysis of vision-language transfer learning for CT enterography, highlighting the effects of pooling strategies and tissue contrast on model performance.

Findings

Mean pooling improves disease classification accuracy.

Attention pooling enhances cross-modal retrieval.

Multi-window RGB encoding outperforms multiplanar sampling.

Abstract

Computed tomography (CT) enterography is a primary imaging modality for assessing inflammatory bowel disease (IBD), yet the representational choices that best support automated analysis of this modality are unknown. We present the first study of vision-language transfer learning on abdominal CT enterography and identify two main findings. First, mean pooling of slice embeddings gives better categorical disease assessment (59.2\% three-class accuracy), whereas attention pooling gives better cross-modal retrieval (0.235 text-to-image MRR). This pattern holds across all LoRA configurations tested and suggests that the two aggregators emphasize different properties of the learned representation. Second, per-slice tissue contrast matters more than broader spatial coverage: multi-window RGB encoding, which maps complementary Hounsfield Unit windows to RGB channels, outperforms all strategies that increase spatial coverage through multiplanar sampling, and in this setting adding coronal and sagittal views reduces classification performance. For report generation, fine-tuning without retrieval context yields within-1 severity accuracy at the prevalence-matched chance level (70.4\% vs.\ 71\% random), suggesting little learned ordering beyond the class distribution. Retrieval-augmented generation (RAG) improves this across all configurations, scoring 7--14 percentage points above the chance baseline and improving ordinal MAE from 0.98 to 0.80--0.89. A three-teacher pseudolabel framework enables all comparisons without expert annotations. Together, these findings provide the first baselines for this underexplored modality and offer practical guidance for building vision-language systems for volumetric medical imaging.