Learning What's Real: Disentangling Signal and Measurement Artifacts in Multi-Sensor Data, with Applications to Astrophysics
Pablo Mercader-Perez, Carolina Cuesta-Lazaro, Daniel Muthukrishna, Jeroen Audenaert, V. Ashley Villar, David W. Hogg, Marc Huertas-Company, William T. Freeman

TL;DR
This paper introduces a deep learning framework that disentangles intrinsic signals from measurement artifacts in multi-sensor data, enabling more accurate scientific analysis and instrument-independent comparisons, demonstrated on astrophysical galaxy images.
Contribution
The proposed method uses overlapping observations, dual-encoder architecture, and counterfactual objectives to explicitly separate physical signals from sensor-specific distortions.
Findings
Effective disentanglement of signals and artifacts in astrophysical data.
Enables counterfactual view generation and unconfounded parameter inference.
Applicable as a general self-supervised pretraining approach for multi-modal data.
Abstract
Data collected from the physical world is always a combination of multiple sources: an underlying signal from the physical process of interest and a signal from measurement-dependent artifacts from the sensor or instrument. This secondary signal acts as a confounding factor, limiting our ability to extract information about the physics underlying the phenomena we observe. Furthermore, it complicates the combination of observations in heterogeneous or multi-instrument settings. We propose a deep learning framework that leverages overlapping observations, a dual-encoder architecture, and a counterfactual generation objective to disentangle these factors of variation. The resulting representations explicitly separate intrinsic signals from sensor-specific distortions and noise, and can be used for counterfactual view generation, parameter inference unconfounded by measurement distortions,…
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