Learning from Many and Adapting to the Unknown in Open-set Test Streams
Xiao Zhang, Juntao Lyu, Tianyu Hu, Qianchuan Zhao, Huimin Ma

TL;DR
This paper introduces SyCo, a parameter-efficient adaptation method for large language models that leverages biological signaling principles to improve performance in open-set, non-stationary test streams.
Contribution
It proposes a novel biologically inspired adaptation technique, SyCo, and a new multi-source open-set adaptation setting for NLP models.
Findings
SyCo outperforms baselines on 18 NLP datasets.
Achieves 78.31% accuracy on unseen-task adaptation.
Achieves 85.37% accuracy on unseen-data shifts.
Abstract
Large Language Models (LLMs) generalize across tasks via reusable representations and flexible reasoning, yet remain brittle in real deployment under evolving tasks and continual distribution shift. A common approach is Test-Time Adaptation (TTA), existing ones of which updates models with hand-designed unsupervised objectives over the full parameter space and mostly overlook preserving shared source knowledge and the reliability of adaptation signals. Drawing on molecular signaling cascades of memory updating in Drosophila, we propose Synapse Consolidation (SyCo), a parameter-efficient LLM adaptation method that updates low-rank adapters through Rac1 and MAPK pathways under the guidance of a structured TTA objective driven by problem understanding, process understanding, and source-domain guardrail. Rac1 confines plasticity to a tail-gradient subspace that is less critical for source…
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