Better than Average: Spatially-Aware Aggregation of Segmentation Uncertainty Improves Downstream Performance
Vanessa Emanuela Guarino, Claudia Winklmayr, Jannik Franzen, Josef Lorenz Rumberger, Manuel Pfeuffer, Sonja Greven, Klaus Maier-Hein, Carsten T. L\"uth, Christoph Karg, Dagmar Kainmueller

TL;DR
This paper investigates how spatially-aware aggregation methods for segmentation uncertainty improve downstream detection tasks, proposing new strategies and a meta-aggregator for robustness across diverse datasets.
Contribution
It formally analyzes existing aggregation strategies, introduces novel spatially-aware methods, and benchmarks their effectiveness, culminating in a meta-aggregator for improved robustness.
Findings
Spatially-aware aggregators outperform traditional methods in downstream tasks.
The effectiveness of aggregation strategies varies with dataset characteristics.
A meta-aggregator combining multiple strategies offers robust performance across datasets.
Abstract
Uncertainty Quantification (UQ) is crucial for ensuring the reliability of automated image segmentations in safety-critical domains like biomedical image analysis or autonomous driving. In segmentation, UQ generates pixel-wise uncertainty scores that must be aggregated into image-level scores for downstream tasks like Out-of-Distribution (OoD) or failure detection. Despite routine use of aggregation strategies, their properties and impact on downstream task performance have not yet been comprehensively studied. Global Average is the default choice, yet it does not account for spatial and structural features of segmentation uncertainty. Alternatives like patch-, class- and threshold-based strategies exist, but lack systematic comparison, leading to inconsistent reporting and unclear best practices. We address this gap by (1) formally analyzing properties, limitations, and pitfalls of…
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