Cost-Aware Optimized Front-Door Experimental Design
Leopold Mareis, Mathias Drton

TL;DR
This paper develops a cost-aware experimental design framework for causal effect estimation in multivariate linear front-door models, optimizing sampling strategies to improve efficiency while considering measurement costs, with proven theoretical properties and practical benefits.
Contribution
It introduces a closed-form optimal sampling policy and estimator for cost-efficient causal effect estimation under unobserved confounding, extending to back-door methods.
Findings
Achieves 5.3% to 31.9% efficiency gains over naive sampling.
Derives the full-data efficient influence function and geometry of influence functions.
Provides a practical optimal sampling policy with theoretical guarantees.
Abstract
Causal effect estimation often succeeds cost-constrained sequential data collection. This work considers multivariate linear front-door models with arbitrary unobserved confounding on treatment and response. We optimize the experimental design by balancing the statistical efficiency and measurement costs through partial data. The full-data efficient influence function for the causal effect is derived, together with the geometry of all observed-data influence functions. This characterization yields a closed-form optimal sampling policy and an estimator to minimize the asymptotic variance of regular asymptotically linear (RAL) estimators within a class of augmented full-data influence functions. The resulting design also covers back-door estimation. In simulations and applications to biological, medical, and industrial datasets, the optimized designs achieve substantial efficiency gains…
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Taxonomy
TopicsAdvanced Causal Inference Techniques · Statistical Methods in Clinical Trials · Statistical Methods and Inference
