Optimal Bilinear control restricted to the three-dimensional chemo-repulsion model with potential production
Francisco Guillen-Gonzalez, Exequiel Mallea-Zepeda, Maria A. Rodriguez-Bellido, Elder J. Villamizar-Roa

TL;DR
This paper investigates the optimal control of a three-dimensional chemo-repulsion PDE system with potential production, establishing existence, regularity, and optimality conditions for controls acting on a subdomain.
Contribution
It introduces a novel analysis of the bilinear control problem for the chemo-repulsion model, proving existence, regularity, and deriving optimality conditions.
Findings
Existence of global weak solutions under certain conditions.
Enhanced regularity results for solutions with specific control spaces.
Derivation of first-order necessary optimality conditions.
Abstract
In this paper we study the following three-dimensional parabolic-parabolic chemo-repulsion model with potential production, logistic reaction and bilinear control, defined in : \begin{equation*}\label{eq0} \left\{ \begin{array}{rcl} \partial_tu-\Delta u&=&\nabla\cdot(u\nabla v)+r\,u-\mu\, u^p,\\ \partial_tv-\Delta v+v&=&u^p+f\,v\, 1_{\Omega_c}, \end{array} \right. \end{equation*} where , , and is the control function acting on a subdomain , with . This system is endowed with initial and non-flux boundary conditions. We prove the existence of global weak solutions of this controlled problem when , analyzing the role of the diffusion and the logistic terms to get energy estimates. In particular, the logistic competition term is…
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Taxonomy
TopicsMathematical Biology Tumor Growth · Mathematical and Theoretical Epidemiology and Ecology Models · Nonlinear Partial Differential Equations
