Sequential Transport for Causal Mediation Analysis
Agathe Fernandes Machado, Iryna Voitsitska, Arthur Charpentier, Ewen Gallic

TL;DR
This paper introduces sequential transport (ST), a novel distributional framework for causal mediation analysis that constructs unit-level counterfactual mediators using optimal transport, avoiding cross-world assumptions and aligning with causal DAGs.
Contribution
ST combines optimal transport with causal DAGs to construct mediator counterfactuals, providing a consistent, distributional approach to causal mediation analysis without relying on cross-world assumptions.
Findings
ST recovers classical mediation formulas in Gaussian cases.
Simulation studies show ST performs well in nonlinear and mixed-type settings.
Application to COMPAS dataset demonstrates DAG-consistent counterfactual mediators.
Abstract
We propose sequential transport (ST), a distributional framework for mediation analysis that combines optimal transport (OT) with a mediator directed acyclic graph (DAG). Instead of relying on cross-world counterfactual assumptions, ST constructs unit-level mediator counterfactuals by minimally transporting each mediator, either marginally or conditionally, toward its distribution under an alternative treatment while preserving the causal dependencies encoded by the DAG. For numerical mediators, ST uses monotone (conditional) OT maps based on conditional CDF/quantile estimators; for categorical mediators, it extends naturally via simplex-based transport. We establish consistency of the estimated transport maps and of the induced unit-level decompositions into mutatis mutandis direct and indirect effects under standard regularity and support conditions. When the treatment is randomized…
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Taxonomy
TopicsBayesian Modeling and Causal Inference · Advanced Causal Inference Techniques · Functional Brain Connectivity Studies
