NeuroLoRA: Context-Aware Neuromodulation for Parameter-Efficient Multi-Task Adaptation
Yuxin Yang, Haoran Zhang, Mingxuan Li, Jiachen Xu, Ruoxi Shen, Zhenyu Wang, Tianhao Liu, Siqi Chen, Weilin Huang

TL;DR
NeuroLoRA introduces a context-aware, neuromodulation-inspired Mixture-of-Experts framework for parameter-efficient multi-task adaptation of large language models, improving task decoupling and continual learning.
Contribution
It proposes a novel neuromodulation-based MoE approach with a contrastive orthogonality loss, enhancing multi-task adaptation and continual learning in LLMs.
Findings
Outperforms FlyLoRA and other baselines on MMLU, GSM8K, and ScienceQA.
Maintains parameter efficiency while improving task decoupling.
Effective in single-task, multi-task, and continual learning scenarios.
Abstract
Parameter-Efficient Fine-Tuning (PEFT) techniques, particularly Low-Rank Adaptation (LoRA), have become essential for adapting Large Language Models (LLMs) to downstream tasks. While the recent FlyLoRA framework successfully leverages bio-inspired sparse random projections to mitigate parameter interference, it relies on a static, magnitude-based routing mechanism that is agnostic to input context. In this paper, we propose NeuroLoRA, a novel Mixture-of-Experts (MoE) based LoRA framework inspired by biological neuromodulation -- the dynamic regulation of neuronal excitability based on context. NeuroLoRA retains the computational efficiency of frozen random projections while introducing a lightweight, learnable neuromodulation gate that contextually rescales the projection space prior to expert selection. We further propose a Contrastive Orthogonality Loss to explicitly enforce…
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Taxonomy
TopicsDomain Adaptation and Few-Shot Learning · Machine Learning in Healthcare · Topic Modeling
