Machine Learning-Based Classification of Jhana Advanced Concentrative Absorption Meditation (ACAM-J) using 7T fMRI

TL;DR

This study demonstrates that machine learning models can classify advanced meditation states (ACAM-J) using fMRI data with moderate accuracy, highlighting neural correlates in prefrontal and anterior cingulate regions.

Contribution

It introduces a machine learning approach to classify ACAM-J meditation states based on ReHo fMRI data, showing potential for neural state identification.

Findings

Ensemble models achieved 66.82% accuracy in classification.

Prefrontal and anterior cingulate regions were most influential.

Moderate agreement indicates feasibility of neural state classification.

Abstract

Jhana advanced concentration absorption meditation (ACAM-J) is related to profound changes in consciousness and cognitive processing, making the study of their neural correlates vital for insights into consciousness and well-being. This study evaluates whether functional MRI-derived regional homogeneity (ReHo) can be used to classify ACAM-J using machine-learning approaches. We collected group-level fMRI data from 20 advanced meditators to train the classifiers, and intensive single-case data from an advanced practitioner performing ACAM-J and control tasks to evaluate generalization. ReHo maps were computed, and features were extracted from predefined brain regions of interest. We trained multiple machine learning classifiers using stratified cross-validation to evaluate whether ReHo patterns distinguish ACAM-J from non-meditative states. Ensemble models achieved 66.82% (p < 0.05) accuracy in distinguishing ACAM-J from control conditions. Feature-importance analysis indicated that prefrontal and anterior cingulate areas contributed most to model decisions, aligning with established involvement of these regions in attentional regulation and metacognitive processes. Moreover, moderate agreement reflected in Cohen's kappa supports the feasibility of using machine learning to distinguish ACAM-J from non-meditative states. These findings advocate machine-learning's feasibility in classifying advanced meditation states, future research on neuromodulation and mechanistic models of advanced meditation.