On the Sequence Reconstruction Problem for the Single-Deletion Two-Substitution Channel
Wentu Song, Kui Cai, and Tony Q. S. Quek

TL;DR
This paper investigates the sequence reconstruction problem for a channel with one deletion and up to two substitutions, providing bounds on the intersection size of error balls and advancing understanding of mixed-error channels.
Contribution
It establishes an upper bound on the intersection size for the single-deletion two-substitution channel and proves its tightness, extending sequence reconstruction theory to mixed-error scenarios.
Findings
Upper bound on intersection size for sequences with Hamming distance d≥2
Bound is tight up to an additive constant
Results apply to q-ary sequences of length n
Abstract
The Levenshtein sequence reconstruction problem studies the reconstruction of a transmitted sequence from multiple erroneous copies of it. A fundamental question in this field is to determine the minimum number of erroneous copies required to guarantee correct reconstruction of the original sequence. This problem is equivalent to determining the maximum possible intersection size of two error balls associated with the underlying channel. Existing research on the sequence reconstruction problem has largely focused on channels with a single type of error, such as insertions, deletions, or substitutions alone. However, relatively little is known for channels that involve a mixture of error types, for instance, channels allowing both deletions and substitutions. In this work, we study the sequence reconstruction problem for the single-deletion two-substitution channel, which allows one…
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Taxonomy
TopicsDNA and Biological Computing · Genome Rearrangement Algorithms · semigroups and automata theory
