On a stochastic phase-field model of cell motility with singular diffusion
Amjad Saef, Wilhelm Stannat

TL;DR
This paper establishes the existence of solutions for a class of stochastic phase-field models used in cell motility, addressing singularities at zero level sets and considering both independent and coupled phase-field evolutions.
Contribution
It proves global existence of probabilistically weak solutions for stochastic reaction-diffusion models with singular diffusion in cell motility applications.
Findings
Proved global existence of solutions for singular stochastic phase-field models.
Addressed technical challenges due to singularities at zero level sets.
Analyzed both independent and coupled phase-field evolutions.
Abstract
We study existence of solutions in the variational sense for a class of stochastic phase-field models describing moving boundary problems. The models consist of stochastic reaction-diffusion equations with singular diffusion forced by a phase-field. We investigate both the case of an independently evolving phase-field and of coupled phase-field evolution driven by a viscous Hamilton-Jacobi equation. Such systems are used in the modelling of single-cell chemotaxis, where the contour of the cell shape corresponds to a level set of the phase-field. The technical challenge lies in the singularities at zero level sets of the phase-field. For large classes of initial data, we establish global existence of probabilistically weak solutions in -spaces with weights which compensate for the singularities.
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Taxonomy
TopicsMathematical Biology Tumor Growth · Solidification and crystal growth phenomena · Stochastic processes and financial applications
