On a Thermodynamically Consistent Diffuse-Interface Model for Incompressible Two-Phase Flows with Chemotaxis and Mass Transport
Andrea Giorgini, Jingning He, Hao Wu

TL;DR
This paper develops a thermodynamically consistent diffuse-interface model for incompressible two-phase flows with chemotaxis and mass transport, establishing existence, uniqueness, and regularity of solutions, and highlighting differences from classical Keller--Segel systems.
Contribution
It introduces a novel model derived from Onsager's principle that couples fluid dynamics, chemotaxis, and mass transport, and provides rigorous mathematical analysis of its solutions.
Findings
Existence of global finite energy solutions in 2D.
Existence and uniqueness of global strong solutions for regular initial data.
Chemical density remains bounded, preventing singularities.
Abstract
We investigate a hydrodynamic system of Navier--Stokes/Cahn--Hilliard type, which describes the motion of a two-phase flow of two incompressible fluids with unmatched densities coupled with a soluble chemical species. Derived from Onsager's variational principle, this thermodynamically consistent diffuse-interface model incorporates both the chemotaxis effects induced by the chemical species and the mass transport processes within the mixture. For the two-dimensional initial-boundary value problem, we establish the existence of global finite energy solutions and global weak solutions, using a suitable approximation scheme combined with compactness methods. Next, by carefully analyzing three decoupled subsystems and employing a bootstrap argument, we prove the existence and uniqueness of a global strong solution for sufficiently regular initial data, as well as the propagation of…
Peer Reviews
No public reviews on file for this paper yet. If you reviewed it on a platform where reviews are public (OpenReview, ICLR, NeurIPS, ICML), you can paste yours below so the community can read it here.
Videos
No videos yet. Explain this paper in a talk, walkthrough, or lecture? Add one.
Taxonomy
TopicsMathematical Biology Tumor Growth · Solidification and crystal growth phenomena · Micro and Nano Robotics
