Blow-up suppression of the Patlak-Keller-Segel-Navier-Stokes system via Taylor-Couette flow
Shikun Cui, Lili Wang, and Wendong Wang

TL;DR
This paper demonstrates that strong Taylor-Couette flow can prevent blow-up in the Patlak-Keller-Segel-Navier-Stokes system, ensuring global boundedness of solutions regardless of initial conditions.
Contribution
It provides a mathematical proof that sufficiently strong Taylor-Couette flow stabilizes the system and prevents blow-up, a novel insight into flow-induced stability mechanisms.
Findings
Strong flow prevents blow-up in the system.
Solutions are globally bounded with large flow strength.
No smallness restriction on initial conditions is needed.
Abstract
Motivated by the use of Taylor-Couette flow in extracorporeal circulation devices [Krfer et al., 2003, 26(4): 331-338], where it leads to an accumulation of platelets and plasma proteins in the vortex center and therefore to a decreased probability of contact between platelets and material surfaces and its protein adsorption per square unit is significantly lower than laminar flow. Increased platelet adhesion or protein adsorption on the device surface can induce platelet aggregation or thrombosis, which is analogous to the ``blow-up phenomenon" in mathematical modeling. Here we mathematically analyze this stability mechanism and demonstrate that sufficiently strong flow can prevent blow-up from occurring. In details, we investigate the two-dimensional Patlak-Keller-Segel-Navier-Stokes system in an annular domain around a Taylor-Couette flow…
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Taxonomy
TopicsMathematical Biology Tumor Growth · Blood properties and coagulation · Lattice Boltzmann Simulation Studies
