Explainable AI For Early Detection Of Sepsis
Atharva Thakur, Shruti Dhumal

TL;DR
This paper introduces an interpretable AI method that combines machine learning with clinical knowledge to accurately predict sepsis onset while providing explanations to enhance clinical trust.
Contribution
It presents a novel interpretable AI approach that integrates clinical knowledge with machine learning for early sepsis detection, improving trust and understanding.
Findings
Accurate prediction of sepsis onset
Enhanced interpretability for clinicians
Alignment with medical expertise
Abstract
Sepsis is a life-threatening condition that requires rapid detection and treatment to prevent progression to severe sepsis, septic shock, or multi-organ failure. Despite advances in medical technology, it remains a major challenge for clinicians. While recent machine learning models have shown promise in predicting sepsis onset, their black-box nature limits interpretability and clinical trust. In this study, we present an interpretable AI approach for sepsis analysis that integrates machine learning with clinical knowledge. Our method not only delivers accurate predictions of sepsis onset but also enables clinicians to understand, validate, and align model outputs with established medical expertise.
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Taxonomy
TopicsSepsis Diagnosis and Treatment · Machine Learning in Healthcare · Artificial Intelligence in Healthcare and Education
