ECGXtract: Deep Learning-based ECG Feature Extraction for Automated CVD Diagnosis

TL;DR

ECGXtract is a deep learning approach that accurately extracts interpretable ECG features for automated cardiovascular disease diagnosis, outperforming existing methods and enabling scalable, resource-efficient clinical applications.

Contribution

The paper introduces ECGXtract, a novel deep learning model capable of extracting multiple ECG features with high interpretability and accuracy, including strategies for multi-feature extraction and model optimization.

Findings

ECGXtract achieves a mean correlation score of 0.80 for global features.

ECGXtract outperforms ECGdeli in 90% of features.

Lead II provides the best results among leads.

Abstract

This paper presents ECGXtract, a deep learning-based approach for interpretable ECG feature extraction, addressing the limitations of traditional signal processing and black-box machine learning methods. In particular, we develop convolutional neural network models capable of extracting both temporal and morphological features with strong correlations to a clinically validated ground truth. Initially, each model is trained to extract a single feature, ensuring precise and interpretable outputs. A series of experiments is then carried out to evaluate the proposed method across multiple setups, including global versus lead-specific features, different sampling frequencies, and comparisons with other approaches such as ECGdeli. Our findings show that ECGXtract achieves robust performance across most features with a mean correlation score of 0.80 with the ground truth for global features, with lead II consistently providing the best results. For lead-specific features, ECGXtract achieves a mean correlation score of 0.822. Moreover, ECGXtract achieves superior results to the state-of-the-art open source ECGdeli as it got a higher correlation score with the ground truth in 90% of the features. Furthermore, we explore the feasibility of extracting multiple features simultaneously utilizing a single model. Semantic grouping is proved to be effective for global features, while large-scale grouping and lead-specific multi-output models show notable performance drops. These results highlight the potential of structured grouping strategies to balance the computational efficiency vs. model accuracy, paving the way for more scalable and clinically interpretable ECG feature extraction systems in limited resource settings.