Ion transport through differently charged nanoporous membranes: from a single nanopore to multi-nanopores

TL;DR

This study systematically investigates how pore charge, number, and spacing influence ion transport in nanoporous membranes, revealing mechanisms of interpore interactions and ion concentration polarization critical for nanofluidic device design.

Contribution

It provides a comprehensive analysis of interpore interactions and ion transport mechanisms in charged nanopore arrays using numerical simulations, advancing membrane design strategies.

Findings

Increased pore number and decreased spacing enhance interpore interactions via ICP.

Bipolar nanopores show negligible ICP and reduced interpore interactions.

Ion current dependence varies with pore charge properties and spacing.

Abstract

Nanoporous membranes, leveraging their high-throughput characteristics, have been widely applied in fields such as molecular separation and energy conversion. Due to interpore interactions, besides the applied voltage and solution environment, the ion transport properties in porous membranes are influenced by the pore number and spacing. Here, to understand and control the transport properties of nanopore arrays, we systematically investigate the ion transport characteristics through membranes with different charge properties, pore numbers, and interpore distances. Using numerical simulations, we analyzed local ionic concentrations and electric potential in nanopore arrays containing nanopores with uniformly charged walls as well as unipolar diodes i.e., pores containing a junction between a charged zone and a neutral zone, and showed significant ion concentration polarization (ICP) for all studied cases. As the number of pores increased and the interpore spacing decreased, the enhanced interpore interactions through ICP led to a greater deviation of the total ionic current from the linear superposition of single-pore currents. Conversely, in bipolar nanopores whose walls contain a junction between positively and negatively charged zones ICP becomes negligible, and interpore interactions are substantially reduced. Furthermore, for membranes with various charge properties, the total current through nanopore arrays presents different quantitative dependence on the pore number under varying pore spacings. Our findings clarify the mechanism of interpore interactions in modulating ion transport through porous membranes, providing critical insights for designing nanofluidic devices based on nanopore arrays, such as nanopore-array sensors.