DentalBench: Benchmarking and Advancing LLMs Capability for Bilingual Dentistry Understanding
Hengchuan Zhu, Yihuan Xu, Yichen Li, Zijie Meng, Zuozhu Liu

TL;DR
DentalBench is a comprehensive bilingual benchmark that evaluates and enhances large language models' capabilities specifically in the dental medical domain, addressing a gap in specialized healthcare AI evaluation.
Contribution
Introduces DentalBench, the first bilingual dental domain benchmark, including a large QA dataset and corpus for domain adaptation, to evaluate and improve LLMs in dentistry.
Findings
Significant performance gaps across models and tasks.
Domain adaptation improves knowledge-intensive task performance.
Highlighting the need for specialized benchmarks in healthcare AI.
Abstract
Recent advances in large language models (LLMs) and medical LLMs (Med-LLMs) have demonstrated strong performance on general medical benchmarks. However, their capabilities in specialized medical fields, such as dentistry which require deeper domain-specific knowledge, remain underexplored due to the lack of targeted evaluation resources. In this paper, we introduce DentalBench, the first comprehensive bilingual benchmark designed to evaluate and advance LLMs in the dental domain. DentalBench consists of two main components: DentalQA, an English-Chinese question-answering (QA) benchmark with 36,597 questions spanning 4 tasks and 16 dental subfields; and DentalCorpus, a large-scale, high-quality corpus with 337.35 million tokens curated for dental domain adaptation, supporting both supervised fine-tuning (SFT) and retrieval-augmented generation (RAG). We evaluate 14 LLMs, covering…
| DentalQA-ZH | DentalQA-EN | |||||||||
| MCQ | MAQ | OEQ | DEF | MCQ | OEQ | DEF | ||||
| Model | ACC | ACC | P | R | F1 | BERTScore | BERTScore | ACC | BERTScore | BERTScore |
| General LLMs | ||||||||||
| GPT-4o | 64.86 | 37.30 | 87.75 | 81.74 | 84.63 | 27.23 | 21.60 | 73.98 | 31.28 | 29.21 |
| GPT-4o-mini | 51.65 | 29.73 | 81.36 | 87.37 | 84.26 | 26.48 | 19.50 | 60.59 | 34.55 | 29.42 |
| Deepseek-V3 | 69.28 | 41.35 | 87.22 | 86.23 | 86.72 | 27.79 | 17.78 | 68.28 | 27.65 | 25.73 |
| Deepseek-R1 | 76.06 | 43.51 | 88.64 | 86.68 | 87.65 | 26.77 | 15.81 | 60.04 | 20.91 | 18.58 |
| Llama-3.2-3B | 38.22 | 7.30 | 72.24 | 65.01 | 68.44 | 19.88 | 15.13 | 48.96 | 28.13 | 26.13 |
| Llama-3.1-8B | 40.80 | 10.27 | 77.45 | 67.49 | 72.13 | 16.69 | 4.96 | 55.60 | 25.31 | 21.75 |
| Qwen2.5-1.5B | 45.58 | 13.24 | 76.67 | 77.55 | 77.11 | 21.74 | 8.57 | 38.09 | 26.10 | 21.59 |
| Qwen2.5-3B | 48.63 | 19.19 | 77.70 | 80.37 | 79.01 | 20.89 | 11.16 | 41.77 | 34.48 | 29.62 |
| Qwen2.5-7B | 60.29 | 26.22 | 83.08 | 79.22 | 81.11 | 26.37 | 11.59 | 49.23 | 26.28 | 22.12 |
| Qwen2.5-14B | 66.48 | 33.51 | 84.05 | 85.01 | 84.53 | 25.47 | 12.69 | 50.49 | 26.68 | 21.93 |
| Qwen2.5-32B | 70.86 | 39.46 | 85.50 | 86.15 | 85.82 | 26.02 | 11.65 | 58.34 | 26.59 | 22.78 |
| Medical LLMs | ||||||||||
| BioMistral-7B | 25.44 | 5.68 | 76.33 | 47.43 | 58.51 | 14.48 | 14.06 | 34.96 | 34.50 | 29.55 |
| HuatuoGPT2-7B | 22.51 | 6.22 | 74.50 | 67.54 | 70.85 | 25.38 | 21.04 | 25.47 | 15.50 | 16.55 |
| Llama-3-8B-UltraMedical | 30.32 | 11.08 | 72.86 | 81.52 | 76.95 | 18.74 | 9.18 | 46.10 | 26.76 | 24.80 |
| Domain Adaptation on Qwen2.5-3B | ||||||||||
| Qwen2.5-3B | 48.63 | 19.19 | 77.70 | 80.37 | 79.01 | 20.89 | 11.16 | 41.77 | 34.48 | 29.62 |
| w. SFT | 54.58 | 25.60 | 75.57 | 93.24 | 83.48 | 22.42 | 15.29 | 47.90 | 37.74 | 30.79 |
| w. RAG | 54.45 | 21.35 | 74.88 | 91.17 | 82.22 | 30.18 | 22.13 | 48.74 | 36.47 | 30.04 |
| w. SFT+RAG | 60.06 | 29.07 | 77.30 | 93.46 | 84.62 | 30.06 | 20.85 | 52.15 | 37.68 | 29.65 |
| Question Format | Content | Mean | Median | Min | Max |
| OEQ-EN | answer | 331.44 | 263 | 58 | 1941 |
| OEQ-EN | question | 147.90 | 108 | 20 | 1498 |
| OEQ-ZH | answer | 182.88 | 149 | 7 | 1321 |
| OEQ-ZH | question | 25.21 | 16 | 6 | 326 |
| DEF-EN | answer | 312.10 | 193 | 46 | 5249 |
| DEF-EN | question | 77.84 | 75 | 24 | 234 |
| DEF-ZH | answer | 59.79 | 52 | 2 | 254 |
| DEF-ZH | question | 22.63 | 22 | 6 | 64 |
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Taxonomy
TopicsNatural Language Processing Techniques · Dental Radiography and Imaging
DentalBench: Benchmarking and Advancing LLMs Capability for
Bilingual Dentistry Understanding
Hengchuan Zhu1, Yihuan Xu1, Yichen Li1, Zijie Meng1, Zuozhu Liu1, 2111Corresponding author.
1Zhejiang University
2ZJU-Angelalign R&D Center for Intelligence Healthcare, Zhejiang, China
{zhuhengchuan1.24, zuozhuliu}@intl.zju.edu.cn
Abstract
Recent advances in large language models (LLMs) and medical LLMs (Med-LLMs) have demonstrated strong performance on general medical benchmarks. However, their capabilities in specialized medical fields, such as dentistry which require deeper domain-specific knowledge, remain underexplored due to the lack of targeted evaluation resources. In this paper, we introduce DentalBench, the first comprehensive bilingual benchmark designed to evaluate and advance LLMs in the dental domain. DentalBench consists of two main components: DentalQA, an English-Chinese question-answering (QA) benchmark with 36,597 questions spanning 4 tasks and 16 dental subfields; and DentalCorpus, a large-scale, high-quality corpus with 337.35 million tokens curated for dental domain adaptation, supporting both supervised fine-tuning (SFT) and retrieval-augmented generation (RAG). We evaluate 14 LLMs, covering proprietary, open-source, and medical-specific models, and reveal significant performance gaps across task types and languages. Further experiments with Qwen-2.5-3B demonstrate that domain adaptation substantially improves model performance, particularly on knowledge-intensive and terminology-focused tasks, and highlight the importance of domain-specific benchmarks for developing trustworthy and effective LLMs tailored to healthcare applications.
**DentalBench: Benchmarking and Advancing LLMs Capability for
Bilingual Dentistry Understanding**
** Hengchuan Zhu1, Yihuan Xu1, Yichen Li1, Zijie Meng1, Zuozhu Liu1, 2111Corresponding author.**
1Zhejiang University
2ZJU-Angelalign R&D Center for Intelligence Healthcare, Zhejiang, China
{zhuhengchuan1.24, zuozhuliu}@intl.zju.edu.cn
1 Introduction
Large Language Models (LLMs) have demonstrated impressive capabilities in a wide range of domains OpenAI et al. (2024); Yang et al. (2025); Liu et al. (2024); Team et al. (2025); DeepSeek-AI et al. (2025); Jaech et al. (2024). Especially in the medical field, recent studies have shown that LLMs can achieve expert-level performance on various clinical benchmarks Wu et al. (2025); Li et al. (2023); Wu et al. (2024); Zhou et al. (2023). However, reliable and fine-grained evaluation of LLM performance in specialized medical subfields-such as dentistry-remain limited, because of the shortage of domain-specific knowledge in general medical corpora or benchmarks.
As an important and highly specialized branch of medicine that spans multiple subfields and involves complex procedures, oral healthcare is in great need of artificial intelligence integration. Although there have been some studies exploring the integration of deep learning techniques into dentistry Shi et al. (2024); Wei et al. (2020); Xiong et al. (2023); Liu et al. (2023), LLMs remain under-evaluated due to the lack of targeted evaluation resources. It hinders not only the understanding of current LLM limitations but also the development of robust systems for clinical applications.
Therefore, in this paper, we introduce DentalBench, a comprehensive benchmark and corpus designed for evaluating and advancing LLM performance in the dental domain. We first construct DentalQA, an English-Chinese question-answering (QA) benchmark covering 4 task formats and 16 specialized subfields. Then, we develop DentalCorpus, a professionally curated bilingual corpus with large-scale and high-quality, aimed at dental-domain adaptation. Using DentalQA, we systematically evaluate various proprietary, open-source and medical-specific LLMs and reveal significant limitations for current models to finish knowledge-intensive tasks in dentistry. Further experiments based on supervised fine-tuning (SFT) and retrieval-augmented generation (RAG) by the DentalCorpus demonstrate that access to in-domain data can substantially improve model performance in specialized oral healthcare tasks, highlighting the importance of benchmarks for domain adaptation in real-world applications. Our main contributions are summarized as follows:
- •
We introduce DentalQA, the first bilingual benchmark for dentistry-specific language understanding, consisting of 36,597 questions across 4 task types and 16 subfields.
- •
We create DentalCorpus, a large-scale, high-quality corpus containing 337.35 million tokens curated for dental domain adaptation with SFT and RAG methods.
- •
We evaluate 14 LLMs—including proprietary, open-source, and medical-specific models—on DentalQA, revealing clear performance gaps across task types and languages. Through extensive experiments, we further demonstrate that domain adaptation with DentalCorpus significantly improves general LLM performance in the dental domain.
2 DentalBench Dataset
We introduce DentalBench, the first comprehensive dataset for evaluating and adapting LLMs in the dental domain, as shown in Figure 1. It consists of: DentalQA, a bilingual benchmark for evaluating knowledge-based reasoning in oral heathcare, and DentalCorpus, a large-scale and high-quality text corpus curated for dental domain adaptation.
2.1 DentalQA
We construct DentalQA, a high-quality English-Chinese benchmark comprising 36,597 questions, covering 4 task formats and 16 dental subfields.
Task Formats. DentalQA includes the following four question types: (a) MCQ: Single-answer multiple choice questions (4 in English, 5 options in Chinese), testing factual recall. (b) MAQ: Multi-answer multiple choice questions (Chinese only), assessing comprehensive diagnostic knowledge. (c) OEQ: Open-ended questions simulating clinical and theoretical scenarios, used to evaluate reasoning and generation. (d) DEF: Terminology definition questions, requiring understanding of domain-specific dental terms.
Domain Coverage. Each question is categorized into one of 16 dental subfields (e.g., oral anatomy, periodontics, orthodontics) based on standard textbook classifications of the 8th round of the National Higher Education Curriculum for Five-Year Undergraduate Dental Medicine Programs (e.g., Zhao et al. (2020)). Figure 1 shows examples across task formats and domain data distributions, with additional details provided in Appendix C.1.
Data Sources. The English dataset is curated from seven public medical QA datasets: MMLU Hendrycks et al. (2021), MedQA Jin et al. (2020), MedMCQA Pal et al. (2022), MedQuAD Ben Abacha and Demner-Fushman (2019), PubMedQA Jin et al. (2019), and iCliniq Regin (2017), Medical Meadow Flashcards and Medical Meadow Wikidoc Yu et al. (2024). Then, we use a keyword list derived from the DentalCorpus filtering process to filter the datasets. Furthermore, we use dental terms from a bilingual glossary compiled from textbooks in the DentalCorpus pipeline and retrieve their definitions from UMLS U.S. National Library of Medicine (2025b) to construct English DEF questions. The Chinese dataset includes questions from the China National Dental Licensing Examination (1999–2021), 34 dental textbooks and auxiliary materials, and 181 OEQs derived from real orthodontist-patient interactions.
Construction. We apply a unified pipeline across both languages. MCQs and MAQs are normalized to fixed option counts. DEF questions are generated by filling 50 predefined templates per language (Appendix A.1) with extracted dental terms and their definitions. OEQs are preserved in their original form without modification. To ensure quality and domain relevance, we use GPT-4o to classify all questions into three categories: oral-related, non-oral, and insufficient (Appendix A.2). The insufficient category is used for questions with incomplete or corrupted content. We filter and retain only the oral-related questions.
Human Validation. To assess classification accuracy, we manually reviewed 300 representative samples—50 for each combination of language and category. The results indicate strong agreement: 100%, 96%, and 94% for English, and 96%, 92%, and 92% for Chinese.
2.2 DentalCorpus
We construct DentalCorpus, a bilingual resource designed to support domain adaptation and retrieval-augmented generation in dentistry.
Data Sources. DentalCorpus is built from three major sources: (a) Textbooks. We collect 40 Chinese dental textbooks and auxiliary materials, remove non-content sections and apply OCR to obtain 4.1M characters of clean text. We also extract a bilingual glossary of 1,971 dental terms from glossaries. (b) PubMed Articles. Using 28 MeSH terms (listed in Appendix B.1), we retrieve 54,651 freely accessible full-text articles from PubMed U.S. National Library of Medicine (2025a), published between 2000 and 2024, yielding 983.3M English and 5.4M Chinese characters. (c) Open Medical Datasets. We filter MMedC Qiu et al. (2024) (EN: 10.56B, ZH: 4.35B tokens) and MedRAG Zhao et al. (2025) (23.9M PubMed snippets) to retain dental-relevant content.
Construction. We implement a rule-based filtering pipeline using keyword lists derived from TF-IDF analysis on dental and general medical corpora. Starting from vocabularies built on PubMed, MedRAG, and textbook texts, we intersect them with the glossary to obtain candidate dental terms. Terms that appear disproportionately in general medical texts are removed. The final filtering lists contain 440 English and 235 Chinese keywords.
Texts from all sources are filtered using these keywords. We apply a keyword density threshold of >1% and require at least two distinct matches per sentence. English is tokenized by spaces; Chinese uses direct string matching.
After filtering, we deduplicate the corpus using MD5 hashes, embed texts with the bge-m3 model, and segment into chunks of up to 512 tokens. The final corpus consists of 1.06M English chunks (319.08M tokens) and 66.3K Chinese chunks (18.27M tokens).
Human Validation. We manually reviewed 100 random samples per language to assess filter quality, confirming domain relevance rates of 99% for English and 96% for Chinese.
3 Experiments
3.1 Experimental Setup
We split DentalQA into training and test sets in a 4:1 ratio while preserving each subfield’s proportions, and report all results on the held-out test set. MCQ performance is measured by Accuracy; MAQ by Accuracy, Precision, Recall and F1; and OEQ and DEF by BERTScore F1 (Zhang et al., 2019). We conduct our experiments on multiple popular LLMs. For general LLMs, we select DeepSeek-V3, DeepSeek-R1, GPT-4o, GPT-4o-mini, LLaMA-3.2-3B-Instruct, LLaMA-3.1-8B-Instruct Grattafiori et al. (2024) and Qwen-2.5-1.5/3B/7B/14B/32B-Instruct Qwen et al. (2025). For medical LLMs, we select BioMistral-7B Labrak et al. (2024), HuatuoGPT2-7B Chen et al. (2024) and LLaMA-3-8B-UltraMedical Zhang et al. (2024). We evaluate in a zero-shot setting using task-specific prompt templates (Appendix A.3). Experiments are conducted on eight NVIDIA RTX 3090 GPUs.
3.2 Domain Adaptation on Qwen2.5-3B
To enhance dentistry-specific knowledge and capabilities, we adopt three adaptation strategies based on Qwen-2.5-3B-Instruct. (a) Supervised Fine-Tuning (SFT): Full-model fine-tuning on the DentalQA training split for four epochs with a learning rate of 1e-6 and batch size 16 using bfloat16 precision. (b) Retrieval-Augmented Generation (RAG): At inference, retrieve the top-5 most relevant passages from DentalCorpus via FAISS with bge-m3 embeddings and prepend them to the prompt (Appendix A.3). (c) SFT + RAG: Combine the above supervised fine-tuning with retrieval augmentation during inference.
3.3 Results
The main results are presented in Table 1, where we report the performance of 14 LLMs and our domain adaptation results.
Overall Trends. Performance varies markedly by language. On DentalBench-ZH, DeepSeek-R1 achieves state-of-the-art accuracy on both MCQ and MAQ, with DeepSeek-V3 and Qwen2.5-32B close behind. Conversely, on DentalBench-EN, GPT-4o leads across these tasks. In both languages, however, open-ended tasks (OEQ and DEF) trail far behind MCQ and MAQ, underscoring enduring challenges in domain-specific generative reasoning and terminology.
General Models vs. Medical Models. Although medical LLMs perform relatively well on OEQ and DEF, they fall markedly short of general-purpose models on MCQ and MAQ. For example, Llama-3.1-8B consistently outperforms its medical counterpart across all multiple-choice tasks, suggesting that medical tuning may insufficiently capture dentistry-specific factual knowledge.
Impact of Model Scale. In the Qwen-2.5 family, scaling improves MCQ and MAQ notably but yields limited gains on OEQ and DEF, suggesting factual recall benefits more from model size than generative reasoning does.
Domain Adaptation. Both SFT and RAG improve MCQ and MAQ, but RAG shows a larger impact on open-ended tasks (e.g., OEQ-ZH BERTScore: +9.29 vs. +1.53). Combining both yields additive gains—especially on MCQ and MAQ (+11.43 and +9.88). For OEQ/DEF, SFT+RAG offers clear benefit over SFT alone in Chinese, while in English the effect is less consistent, indicating language sensitivity in retrieval effectiveness.
4 Conclusion
We introduce DentalBench, a comprehensive bilingual benchmark designed for evaluating and enhancing LLMs in the dental domain. It includes 2 main components: DentalQA, the first bilingual high-quality QA dataset for dentistry, and DentalCorpus, a large-scale domain-specific English-Chinese corpus for domain adaptation, such as SFT and RAG. Our experiments across 14 LLMs, covering proprietary, open-source and medical-specific models, reveal significant performance gaps based on task types, language, and model categories. Additionally, through extensive experiments, we demonstrate that domain adaptation using DentalCorpus can significantly improve performance. In general, DentalBench can be served as a valuable resource for evaluating knowledge-grounded language models in dentistry, improving language understanding in oral healthcare, and encouraging more related research.
Limitations
Our work has several limitations. First, the dataset exhibits asymmetry between Chinese and English sources. While both languages are supported throughout DentalQA and DentalCorpus, the distribution, source diversity, and depth of coverage are not fully aligned—potentially contributing to observed cross-lingual performance gaps. Second, the MAQ format is currently only available in Chinese, limiting comprehensive evaluation of multi-answer reasoning capabilities in English. In future work, we aim to construct balanced bilingual resources and expand task coverage across languages.
Appendix A Dataset Construction Prompts & Templates
A.1 Definition Templates
Fig. 2 and Fig. 3 list the 50 instruction templates used to construct DEF questions from domain terms in English and Chinese.
A.2 Filtering Classification Prompt
Fig. 4 shows the prompt for classifying questions into oral-related, non-oral, or insufficient categories.
A.3 Evaluation and RAG Prompts
Fig. 5 shows the prompt formats used to evaluate different question types in zero-shot settings and the prompt format with RAG.
Appendix B Corpus Construction Details
B.1 MeSH Terms for PubMed Query
Fig. 6 is the list of 28 MeSH terms used to retrieve relevant dental articles from PubMed.
Appendix C Dataset Statistics and Visualizations
C.1 Distribution by Task and Subfield
Fig. 7 shows the distribution of DentalQA by task and subfield.
C.2 Answer Properties and Input Lengths
Fig. 5 shows the prompt formats used to evaluate different question types in zero-shot settings and the prompt format with RAG.
C.3 Supplementary Performance Figures
Extended plots (8, 9, 10, 11, 12, 13, 14, 16, 17) complementing Section 1, including per-model and per-task visual comparisons.
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