Implementing Zero Trust Architecture to Enhance Security and Resilience in the Pharmaceutical Supply Chain
Saeid Ghasemshirazi, Ghazaleh Shirvani, Marziye Ranjbar Tavakoli, Bahar Ghaedi, Mohammad Amin Langarizadeh

TL;DR
This paper explores how implementing Zero Trust Architecture can significantly improve cybersecurity and resilience in the pharmaceutical supply chain, addressing threats like data breaches and counterfeiting.
Contribution
It introduces zero trust principles tailored for pharmaceutical supply chains and demonstrates their effectiveness through real-world case studies.
Findings
Enhanced security and data protection in pharmaceutical supply chains
Successful implementation of zero trust principles in real-world scenarios
Improved resilience against cyber threats and operational disruptions
Abstract
The pharmaceutical supply chain faces escalating cybersecurity challenges threatening patient safety and operational continuity. This paper examines the transformative potential of zero trust architecture for enhancing security and resilience within this critical ecosystem. We explore the challenges posed by data breaches, counterfeiting, and disruptions and introduce the principles of continuous verification, least-privilege access, and data-centric security inherent in zero trust. Real-world case studies illustrate successful implementations. Benefits include heightened security, data protection, and adaptable resilience. As recognized by researchers and industrialists, a reliable drug tracing system is crucial for ensuring drug safety throughout the pharmaceutical production process. One of the most pivotal domains within the pharmaceutical industry and its associated supply chains…
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