Towards a better understanding of abdominal wall biomechanics: in vivo relationship between dynamic intra-abdominal pressure and magnetic resonance imaging measurements

TL;DR

This study investigates the in vivo relationship between intra-abdominal pressure and abdominal wall movement using MRI and pressure sensors, revealing participant-specific behaviors crucial for personalized hernia treatment and surgical planning.

Contribution

It provides the first detailed analysis of how intra-abdominal pressure correlates with abdominal wall displacement during different exercises, highlighting the importance of personalized assessments.

Findings

Strong correlation between rectus abdominis displacement and pressure during breathing

Lateral muscle displacement correlates with pressure during coughing and Valsalva

Participant-specific variability in abdominal compliance during muscular contraction

Abstract

Background In vivo mechanical behaviour of the abdominal wall has been poorly characterised and important details are missing regarding the occurrence and post-operative recurrence rate of hernias which can be as high as 30 %. This study aimed to assess the correlation between abdominal wall displacement and intra-abdominal pressure, as well as abdominal compliance. Methods Eighteen healthy participants performed audio-guided passive (breathing) and active (coughing, Valsalva maneuver) exercises. Axial dynamic changes of abdominal muscles and visceral area were measured using MRI, and intra-abdominal pressure with ingested pressure sensor. Findings Correlations between abdominal wall displacement and intra-abdominal pressure were specific to participant, exercise, and varying between rectus abdominis and lateral muscles. Strong correlations were found between rectus abdominis displacement and intra-abdominal pressure during breathing (r = 0.92 $\pm$ 0.06), as well as lateral muscles displacement with intra-abdominal pressure during coughing and Valsalva maneuver (r = --0.98 $\pm$ 0.03 and -- 0.94 $\pm$ 0.05 respectively). The abdominal pseudo-compliance varied greatly among participants during muscular contraction, the coefficient of variation reaching up to 70 %. Interpretation The combination of intra-abdominal pressure and dynamic MRI measurements enables the identification of participant-specific behaviour pattern. Intra-abdominal pressure and abdominal wall dynamic undergo consistent and predictable interactions. However, this relationship is subject-specific and may not be extrapolated to other individuals. Therefore, both intra-abdominal pressure and abdominal wall motion must be measured in the same participant in order to accurately characterise the abdominal wall behaviour. These results are of great importance for mesh design, surgical decision-making, and personalised healthcare.