Not Yet AlphaFold for the Mind: Evaluating Centaur as a Synthetic Participant
Sabrina Namazova, Alessandra Brondetta, Younes Strittmatter, Matthew Nassar, Sebastian Musslick

TL;DR
This paper evaluates Centaur, a large language model fine-tuned on human data, for its potential as a human-like participant simulator in cognitive science, highlighting its strengths and current limitations.
Contribution
It provides a critical assessment of Centaur's capabilities as a participant simulator, identifying key gaps between its predictive accuracy and generative behavior.
Findings
Centaur predicts human behavior accurately in some tasks.
Its generative behavior diverges from actual human data.
It does not yet meet standards for reliable participant simulation.
Abstract
Simulators have revolutionized scientific practice across the natural sciences. By generating data that reliably approximate real-world phenomena, they enable scientists to accelerate hypothesis testing and optimize experimental designs. This is perhaps best illustrated by AlphaFold, a Nobel-prize winning simulator in chemistry that predicts protein structures from amino acid sequences, enabling rapid prototyping of molecular interactions, drug targets, and protein functions. In the behavioral sciences, a reliable participant simulator - a system capable of producing human-like behavior across cognitive tasks - would represent a similarly transformative advance. Recently, Binz et al. introduced Centaur, a large language model (LLM) fine-tuned on human data from 160 experiments, proposing its use not only as a model of cognition but also as a participant simulator for "in silico…
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Taxonomy
TopicsCell Image Analysis Techniques · Language and cultural evolution · Biomedical Text Mining and Ontologies
