Toward Scalable Patient Safety Training: A Prototype for Root Cause Analysis Simulation With AI Virtual Avatars
Yuqi Hu, Qiwen Xiong, Zhenzhen Qin, Brandon Watanabe, Yujing Wang, Mirjana Prpa, Ilmi Yoon

TL;DR
This paper introduces an AI-powered simulation platform using virtual avatars and large language models to enable scalable, immersive patient safety training through root cause analysis, reducing resource requirements.
Contribution
The paper presents a novel Unity-based simulation environment with AI avatars and automated assessment, enhancing scalability and realism in patient safety training.
Findings
Feasibility of integrating generative AI into immersive simulations
Supports scalable training with low instructional burden
Provides automated, rubric-guided feedback
Abstract
Patient safety training is essential for preparing healthcare professionals to identify, investigate, and prevent adverse events. However, conventional simulation-based approaches often require substantial faculty time, physical resources, and standardized facilitation. This paper presents a prototype AI-powered simulation platform designed to support more scalable patient safety training through root cause analysis (RCA). The system provides a Unity-based 3D simulation environment, which allows trainees to investigate an ICU adverse event by interviewing five virtual team members represented as AI-powered avatars. Each avatar is driven by a large language model (LLM) agent with role-specific knowledge and variable states of mind. Moreover, emotional text-to-speech and AI-supported facial and body animation enable more realistic and immersive interactions. After completing the…
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