Multimodal AI for Gastrointestinal Diagnostics: Tackling VQA in MEDVQA-GI 2025
Sujata Gaihre, Amir Thapa Magar, Prasuna Pokharel, and Laxmi Tiwari

TL;DR
This paper presents a multimodal AI approach using the Florence model for visual question answering in gastrointestinal endoscopy, demonstrating promising results and establishing a baseline for future clinical applications.
Contribution
It introduces a novel VQA pipeline leveraging the Florence multimodal model with domain-specific augmentations for medical endoscopy images.
Findings
Fine-tuning Florence achieves high accuracy on challenge metrics.
Domain-specific augmentations improve model generalization.
The approach provides a strong baseline for future medical VQA research.
Abstract
This paper describes our approach to Subtask 1 of the ImageCLEFmed MEDVQA 2025 Challenge, which targets visual question answering (VQA) for gastrointestinal endoscopy. We adopt the Florence model-a large-scale multimodal foundation model-as the backbone of our VQA pipeline, pairing a powerful vision encoder with a text encoder to interpret endoscopic images and produce clinically relevant answers. To improve generalization, we apply domain-specific augmentations that preserve medical features while increasing training diversity. Experiments on the KASVIR dataset show that fine-tuning Florence yields accurate responses on the official challenge metrics. Our results highlight the potential of large multimodal models in medical VQA and provide a strong baseline for future work on explainability, robustness, and clinical integration. The code is publicly available at:…
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