An Algorithm for Identifying Interpretable Subgroups With Elevated Treatment Effects
Albert Chiu

TL;DR
This paper presents an algorithm that identifies interpretable subgroups with high treatment effects using rule sets, aiding decision-making and understanding in treatment effect analysis.
Contribution
The method introduces a novel objective balancing subgroup size and effect size, producing Pareto optimal rule sets for interpretable subgroup identification.
Findings
Produces interpretable rule sets capturing high-order interactions
Offers a Pareto frontier of optimal subgroups balancing size and effect
Demonstrates utility through simulated and empirical examples
Abstract
We introduce an algorithm for identifying interpretable subgroups with elevated treatment effects, given an estimate of individual or conditional average treatment effects (CATE). Subgroups are characterized by ``rule sets'' -- easy-to-understand statements of the form (Condition A AND Condition B) OR (Condition C) -- which can capture high-order interactions while retaining interpretability. Our method complements existing approaches for estimating the CATE, which often produce high dimensional and uninterpretable results, by summarizing and extracting critical information from fitted models to aid decision making, policy implementation, and scientific understanding. We propose an objective function that trades-off subgroup size and effect size, and varying the hyperparameter that controls this trade-off results in a ``frontier'' of Pareto optimal rule sets, none of which dominates the…
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Taxonomy
TopicsMedical and Biological Sciences
